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90-120 / 1000+ resultsresearch HOXC8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression, and Wnt/β-catenin signaling
This study found that misexpression of Hoxc8 in mice led to ectopic mammary development and suggests Hox genes may play crucial roles in the regional specification and initiation of cutaneous accessory organs.
research Hox in hair growth and development
research Hair cortisol: an indicator of HPA activity in relation to environmental perception in New Zealand White rabbit.
This study observed fluctuations in hair cortisol levels in rabbits, indicating their HPA axis activity responded similarly to surgical and environmental stressors, suggesting potential anthropomorphic evaluations of stress.
research Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis
This study found that Krox20 marks a diverse stem cell population in mouse hair follicles, which significantly contributes to the interfollicular epidermis and regulates epidermal homeostasis.
research Organ function is preserved despite reorganization of niche architecture in the hair follicle
research A RARE ENCOUNTER
This case study highlights a testosterone- and cortisol-secreting adrenal oncocytic neoplasm in an 18-year-old woman, illustrating the role of surgical excision in resolving hyperandrogenism and restoring menstruation.
research HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression
This study demonstrated that HOXC13 directly influences hair keratin gene expression by binding to specific DNA motifs, suggesting its role in early hair follicle differentiation.
research Human hair follicle organ culture: theory, application and perspectives
This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.
research The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells
This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.
research Hox in the Niche Controls Hairy-geneity
This study shows that differences in Hoxc gene expression in hair follicle mesenchyme along the body axis contribute to regional variations in mammalian hair growth.
research Hair cortisol in drug-naïve first-episode individuals with psychosis
This study observed that drug-naïve first-episode psychosis patients had higher hair cortisol concentrations than healthy controls, and these concentrations correlated with the severity of psychopathology.
research Hoxc13 and the development of hair follicle
This review summarizes the role of Hoxc13 in regulating hair follicle development and growth, noting its influence on keratin and keratin-associated proteins, and reports no new experimental findings.
research Connective tissue sheath of hair follicle is a major source of dermal type I procollagen in human scalp
The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.
research Fine Structure of the Fully Keratinized Hair Cuticle in the Head Hair of the Human
This article describes the structure and components of hair cuticle cells and their intercellular junctions but reports no new clinical results.
research Parity-related variation in cortisol concentrations in hair during pregnancy and in the postpartum period: a prospective cohort study
This study observed that pregnant women experienced an increase in hair cortisol concentrations, with primiparae having significantly higher levels in the last trimester compared to multiparae.
research 1346 Functional roles of Krox20 (Egr2) in Epithelial Stem Cells
This study found that KROX20 is crucial for hair follicle development and epidermal homeostasis, as its deletion in skin epithelial cells led to hair loss and increased epidermal thickness.
research Hair cortisol concentrations in mental disorders: A systematic review
This review found that patients with depression generally have higher hair cortisol concentrations compared to healthy controls, while those with PTSD tend to have lower concentrations.
research 50285 Oxytocin receptor is present in keratinocytes near touch and pain sensory neurons
This study reports that oxytocin receptor expression in keratinocytes shows a potential relationship with touch sensory neurons, suggesting a role in skin sensitivity and the broader function of sensory neurons.
research 562 Neuroendocrinology of human scalp hair follicles: Growth hormone-releasing hormone (GHRH) stimulates hair growth and controls a fully functional intrafollicular hypothalamic-pituitary-somatotropic (HPS) signaling axis
This study found that human scalp hair follicles produce neurohormones and responded to GHRH stimulation by prolonging hair growth, suggesting a functional peripheral HPS neuroendocrine signaling axis in the skin.
research Coronal approach for rehabilitative orbital decompression in Graves' ophthalmopathy
This study found that three wall orbital decompression by the coronal approach effectively reduces proptosis in Graves' ophthalmopathy patients with fewer complications compared to other techniques.
research Hair Cortisol: A Biomarker of Chronic Stress in Animals and its Association with Reproduction
This article reviews the use of hair cortisol concentration as a biomarker to assess long-term stress in both animals and humans, but it reports no new experimental results.
research Human Hair Follicles Operate a Functional Peripheral Equivalent of the Hypothalamic-Pituitary-Somatotropic Axis Ex Vivo
This article discusses the role of human scalp hair follicles in neurohormone production and their model potential for studying neuroendocrine signaling, reporting no experimental results.
research Organotypic Skin Culture
This article reviews organotypic skin culture systems and their applications in dermatological research, highlighting their ability to model human epidermal conditions in vitro, but it reports no new clinical results.
research The crest phenotype in domestic chicken is caused by a 195 bp duplication in the intron of HOXC10
This study identified a 195 bp duplication in crested chickens that causes large crest feathers and can be associated with cerebral hernia in some breeds, but not all.
research Culture of hair matrix and follicular keratinocytes
research IDENTIFICATION OF RELAY CELLS AND INTERNEURONS IN THE CUNEATE NUCLEUS
The cuneate nucleus has two main neuron types: relay neurons and interneurons.
research Rare Case of Cutis Vertex Gyrata
In this case report, a 21-year-old male was observed to have primary essential cutis verticis gyrata, a condition characterized by the excessive formation of scalp folds resembling cerebral gyri, without any additional comorbidities.
research Ultrastructural and immunohistochemical characteristics of telocytes in human scalp tissue
This study found that telocytes in human scalp tissue were located around hair follicles and glands and may be involved in skin regeneration and homeostasis.
research Three-dimensional architecture of macrofibrils in the human scalp hair cortex
This study observed that human hair macrofibrils predominantly exhibit a double-twist architecture with varying inter-macrofibril angles, advancing insights into their structural organization and mechanical implications.