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Certain inhibitors applied to the skin can promote hair growth by maintaining a key hair growth signal.

Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.

New scaffold materials help heal severe skin wounds and improve skin regeneration.

Future research should focus on making bioengineered skin that completely restores all skin functions.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

A woman's hair loss was caused by her husband's testosterone gel and a diabetic man's nail disease led to bone infection, both treated successfully.

The document concludes that a deeper understanding of skin aging and photodamage is needed to create better skin treatments.

Women and men experience different quality of life and symptom distress after kidney transplant with immunosuppressive therapy.

Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.

Skin problems are common in thyroid disorders, with dry skin in hypothyroidism and warm, soft skin in hyperthyroidism.

Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.

The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

New treatments for hair loss, fertility, and wound healing are being explored.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Androgens can cause hair growth in some areas and hair loss on the scalp.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Different types of stem cells and their environments are key to skin repair and maintenance.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Prolactin affects hair growth cycles and can cause early hair follicle regression.