This review discusses the off-label use of drugs like Minoxidil, Aripripazole, and others, providing insights for physicians and pharmacists but reports no new clinical findings.
54 citations
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March 2024 in “Journal of Medicinal Chemistry” This article summarizes the properties, synthesis, and biomedical applications of molecules with N-oxide functionalities, emphasizing their growing role in healthcare due to their unique properties, such as water solubility and redox reactivity, crucial for drug targeting and cytotoxicity.
14 citations
,
September 2015 in “Expert Opinion on Therapeutic Targets” This review discusses potential treatments for androgen excess in polycystic ovary syndrome and reports no new findings, emphasizing the importance of individualized antiandrogenic management to minimize side effects.
28 citations
,
August 2009 in “Nursing for Women's Health” This review highlights that while healthcare providers are starting to diagnose polycystic ovary syndrome earlier in teens, the psychological and social needs often remain inadequately addressed.
1 citations
,
January 2014 in “Turkish Journal of Ophthalmology” This case report highlights a rare side effect of prostaglandin analogues, detailing prostaglandin-associated periorbitopathy in three glaucoma patients treated with bimatoprost and travoprost.
1 citations
,
April 2022 in “International journal of Ayurveda and pharma research” This case study reports on an Ayurvedic treatment approach for a 22-year-old woman with Polycystic Ovarian Disease showing symptomatic relief and improvements in ultrasound findings.
1 citations
,
May 2013 in “Oncology Times” This narrative review reflects on the challenges faced by FDA's Oncologic Drugs Advisory Committee members, highlighting public pressure, decision-making complexity, and the evolving landscape of cancer drug development.
September 2002 in “Comprehensive Therapy” Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.
This paper suggests that women with acne should be screened for PCOS to enable early treatment and prevent associated risk factors.
July 2023 in “CRC Press eBooks” This chapter reviews various ayurvedic formulations for managing PCOS symptoms but presents no new research findings, suggesting further detailed exploration of their efficacy through an ayurvedic perspective.
35 citations
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July 2009 in “Optics express” This study introduces a new intracavity frequency modulation technique for tunable picosecond optical parametric oscillators, enhancing chemical contrast in coherent Raman imaging by allowing real-time subtraction of background signals.
January 2025 in “Human Reproduction Open”
21 citations
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September 2016 in “Journal of Dermatological Treatment” This article proposes a new classification, the Obsessive-Compulsive Insight Continuum, to help dermatologists better understand and diagnose skin disorders with obsessive-compulsive features.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, FOL-026, a peptide based on osteopontin, was shown to promote angiogenesis and stimulate vascular cell proliferation and migration through neuropilin-1, similar to VEGF, suggesting potential therapeutic applications in vascular repair and angiogenesis-related conditions.
In this prospective observational study at a tertiary care center in Uttar Pradesh, researchers observed that comprehensive, individualized treatments significantly improved clinical outcomes for South Asian women with PCOS, including reductions in BMI and improvements in insulin sensitivity, ovulation, and pregnancy rates.
7 citations
,
February 2023 in “Obesity” This study found that women with PCOS were more likely than women without PCOS to have multiple weight-loss attempts and perceive themselves as overweight, regardless of their actual obesity status.
5 citations
,
April 2013 in “Current Problems in Pediatric and Adolescent Health Care” This review discusses the prevalence and management of polycystic ovary syndrome in women, particularly noting gaps in understanding its presence in adolescents, and reports no new clinical findings.
2 citations
,
June 2024 in “Anti-Aging Eastern Europe” This review discusses the varied clinical presentations and management challenges of Polycystic Ovary Syndrome across different life stages, reporting no new clinical findings.
2 citations
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June 2014 in “مجلة مركز بحوث التقنيات الاحيائية” This study reported that patients with PCOS and thyroid hormone disturbances had specific TPO gene mutations and differing thyroid hormone levels compared to those without disturbances or healthy controls.
12 citations
,
December 2017 in “Gynecological Endocrinology” This study found that the prevalence of PCOS in Thai adolescents was 5.29%, with moderate acne identified as the strongest associated risk factor.
2 citations
,
December 2014 in “Journal of primary health care” This review of polycystic ovary syndrome cases in New Zealand suggests a need for improved recording of diagnostic criteria, as general practitioners often rely on ultrasounds despite guidelines advising otherwise.
9 citations
,
February 2002 in “PubMed” This study identified a novel mutation in the coproporphyrinogen oxidase gene, contributing to hereditary coproporphyria in a family, with decreased enzyme activity observed in the affected members.
April 2022 in “Reproductive health of woman” This article reviews the diagnostic challenges of polycystic ovary syndrome in adolescents, discussing criteria, symptoms overlap with normal puberty, and treatment strategies, but it reports no new clinical findings.
May 2026 in “Advances in Therapy” This paper emphasizes the importance of holistic and compassionate management of obesity and PCOS in adolescent girls, advocating for improved healthcare prioritization and environmental reform to address complex challenges during adolescence.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This report reviews the causes, symptoms, diagnosis, complications, and treatment options for Polycystic Ovarian Disease, emphasizing the importance of early diagnosis and individualized management, but it does not provide new research findings.
49 citations
,
July 2000 in “Journal of Histochemistry & Cytochemistry” This study found cell-specific variations in POMC mRNA and peptide expression in murine skin, suggesting that PC1 and PC2 convertases contribute to differential POMC processing.
37 citations
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January 1986 in “Carcinogenesis” This study found that TPA treatment transiently induces high levels of ODC in mouse epidermal cells, particularly around hair follicles, with localization reduced by retinoic acid or cycloheximide pretreatment.
This study concluded that a formulated herbal suspension containing selected home remedial herbs was effective for the prevention and treatment of polycystic ovary syndrome in an animal model.
7 citations
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August 2017 in “European journal of endocrinology” This study suggests that mutations in exon 10 of the POC1A gene may be linked to a distinct clinical condition characterized by extreme insulin resistance and short stature, differing from SOFT syndrome.
65 citations
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October 2015 in “Acta Biomaterialia” This study found that using a pH-sensitive layered double hydroxide nanocarrier to deliver etoposide significantly reduced liver toxicity and enhanced the drug’s effectiveness in targeting and suppressing non-small cell lung cancer.