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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.