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Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Biotin helps regulate proteins in the blood, which may explain its role in hair growth.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Minoxidil promotes hair growth but stops working when discontinued.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Finasteride and minoxidil work best together for hair loss.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.