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Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

The document explains how male reproductive hormones work and affect the body.

Adult stem cells from rat whisker follicles can regenerate hair follicles and sebaceous glands.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Sp6 promotes tooth development by reducing follistatin levels.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Low TRPS1 expression in skin and hair cells is linked to hair problems in Trichorhinophalangeal syndrome.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.

Sex steroids affect the MafB gene differently in male and female hamsters.

Scientists can now create skin with hair by reprogramming cells in wounds.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Enzymes called PADIs play a key role in hair growth and loss.

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Eating too much or too little vitamin A can cause hair loss.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

Cetaceans lost hair due to changes in the Hr and FGF5 genes.