October 2025 in “Actualización en Medicina de Familia” This review discusses several new pharmacological products, including those for cardiovascular prevention and overactive bladder, but notes challenges in defining their therapeutic roles and provides safety updates on existing medications; it reports no new clinical results.
6 citations
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February 1996 in “Clinical Pharmacology & Therapeutics” Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.
61 citations
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March 1981 in “Circulation” Minoxidil improves blood flow in heart failure patients.
August 2026 in “LUMEN ET VIRTUS” In this study, low-dose oral minoxidil for androgenetic alopecia was generally safe, showing small average changes in blood pressure and heart rate with infrequent cardiovascular issues, though monitoring is essential, especially in patients with conditions like hypertension or arrhythmias.
55 citations
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March 1973 in “PubMed” Minoxidil is a new drug that lowers blood pressure.
100 citations
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March 1973 in “American Journal of Cardiology” Minoxidil effectively lowers blood pressure without major side effects.
11 citations
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January 1980 in “Southern Medical Journal” This study found that minoxidil effectively manages various types of severe hypertension but can cause side effects such as sodium retention and tachycardia.
28 citations
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August 2013 in “Hypertension” The authors concluded that diazoxide reduces undesirable side effects compared to minoxidil while increasing elastic fiber content and decreasing cell number in the aorta, suggesting potential suitability for treating vascular conditions with low arterial elastin and hypertension.
1 citations
,
June 2023 in “Frontiers in Pharmacology” This study found that hydralazine and minoxidil, two direct vasodilators, may worsen abdominal aortic aneurysm progression by increasing aortic degeneration and inflammation.
8 citations
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January 2011 in “Korean Journal of Andrology” This study found that combining 4 mg doxazosin with 0.2 mg tamsulosin improved urinary symptoms with fewer vasodilatory side effects compared to a higher dose of doxazosin in hypertensive males with LUTS.
March 2026 in “Archives of Dermatological Research” Amlodipine cream may help hair growth by improving blood flow.
19 citations
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May 1979 in “Archives of internal medicine” Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.
March 2007 in “Journal of hypertension” Minoxidil effectively lowers blood pressure in patients with resistant hypertension.
Minoxidil can cause hair growth as a side effect.
October 2023 in “Journal of The American Academy of Dermatology” This article discusses the use of low-dose oral minoxidil as an off-label treatment for androgenetic alopecia but reports no new clinical results.
March 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil doesn't affect blood pressure in patients taking blood pressure meds.
February 2023 in “Clinical Toxicology” This letter to the editor raises concerns about minoxidil, an arterial vasodilator also used for androgenic alopecia, noting that overdose can cause severe side effects such as distributive shock, pulmonary edema, and myocardial ischemia.
6 citations
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February 2025 in “International Journal of Molecular Sciences” This study found that the solid self-nanoemulsifying drug delivery system improved the oral bioavailability of carvedilol significantly compared to the drug alone, enhancing its solubility, dissolution, AUC, and Cmax.
9 citations
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March 1989 in “The BMJ” Adding diltiazem to a beta blocker can cause dangerously slow heart rates.
24 citations
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October 2008 in “International Braz J Urol” In this study, short-term treatment with lovastatin showed no effect on symptom severity, prostate volume, or PSA levels in men with prostatic enlargement from presumed benign prostatic hyperplasia.
March 2024 in “Journal of the American Academy of Dermatology” February 2006 in “Inpharma Weekly”
1 citations
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June 2021 in “General physiology and biophysics” In this study, minoxidil-induced vasodilation in rat aorta was found to be mediated by ATP-sensitive potassium channels and nitric oxide pathways, but was not significantly altered by lipid emulsion pretreatment.
1 citations
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September 2023 in “Dermatology online journal” This study highlights the complex clinical issues associated with using low dose oral minoxidil for alopecia, emphasizing the need for careful cardiology-dermatology collaboration due to rare but serious cardiovascular risks, especially in patients with existing cardiorenal or cardiovascular concerns.
109 citations
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July 1984 in “Circulation” This study found that long-term minoxidil treatment, despite improving hemodynamics and left ventricular function, was associated with more frequent clinical events and a poorer clinical course in patients with chronic left ventricular failure.
November 2003 in “PubMed” 6 citations
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January 1977 in “PubMed” This study found that minoxidil, used with beta-blockers and thiazides, effectively reduced blood pressure in patients with severe hypertension, although it required careful management of side effects like sodium retention and increased hair growth.
June 1982 in “Reactions (Auckland)” Metoprolol and propranolol may cause hair loss.
January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu” This study suggested that minoxidil's neuroprotective effect in mice was independent of its blood pressure-lowering action, unlike the effects observed with losartan and doxazosin.
19 citations
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December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study found that multiple ion channel modulators, used here at clinical concentrations, increased intracellular calcium release in prostate and breast cancer cell lines.