122 citations
,
April 1995 in “Journal of Cutaneous Pathology” The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.
34 citations
,
June 2007 in “The Journal of Dermatology” This study observed that non-scarring diffuse hair loss was common in systemic lupus erythematosus patients, but did not find a significant relationship with the SLE Disease Activity Index.
32 citations
,
December 2017 in “International Journal of Molecular Sciences” This review suggests that decreased serum 25-hydroxyvitamin D levels may play a role in different types of non-scarring alopecia, but further studies are needed to explore vitamin D supplementation as a therapeutic option.
30 citations
,
October 2013 in “Lupus” This study identified distinct clinical and dermatoscopic features to differentiate non-scarring patchy alopecia in SLE from alopecia areata, emphasizing the value of serological tests in diagnosis.
29 citations
,
July 2008 in “Journal of Cutaneous Pathology” This study found that follicular streamers are mostly present in non-scarring alopecia cases, and tracking their location can improve diagnosis accuracy.
28 citations
,
January 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” This study found that Greek adult women with scarring alopecia experience more significant psychological burden and quality of life impairment compared to those with non-scarring alopecia.
28 citations
,
June 2007 in “Journal of Cutaneous Pathology” This study found that premature desquamation of the inner root sheath is a non-specific histologic feature in scarring alopecia and cannot be used alone to define central centrifugal cicatricial alopecia.
27 citations
,
September 2017 in “Archives of Dermatological Research” In this study, topical tofacitinib significantly increased hair regrowth in mice compared to minoxidil or vehicle, potentially due to elevated VEGF levels and reduced inflammation.
25 citations
,
March 2017 in “Journal of Dermatological Treatment” This review found that the current evidence on using platelet rich plasma to treat non-cicatricial alopecia, such as androgenetic alopecia and alopecia areata, is of low quality and yields controversial results.
24 citations
,
September 2018 in “Lasers in Surgery and Medicine” This study shows that multiphoton microscopy can non-invasively distinguish between scarring and non-scarring alopecia by identifying certain morphological features, but further research is needed to confirm its clinical utility.
19 citations
,
May 2021 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the progress in research on topical formulations for treating alopecia, highlighting potential advantages of advanced formulation technologies but reporting no new clinical results.
19 citations
,
June 2020 in “International Journal of Dermatology” In this systematic review, oral minoxidil was found to be a safe and effective treatment for androgenetic alopecia and alopecia areata, with additional benefits for female pattern hair loss and other types of alopecia, although common side effects included hypertrichosis and postural hypotension.
17 citations
,
May 2016 in “Archives of Dermatological Research” This study identified specific reflectance confocal microscopy features that help differentiate scarring from non-scarring alopecia, providing a non-invasive diagnostic tool.
4 citations
,
August 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil does not cause tachycardia in hair loss patients.
4 citations
,
January 2023 in “Frontiers in Immunology” In this Mendelian randomization study, shortened leukocyte telomere length was associated with an increased risk of androgenetic alopecia, but no causal relationship was found with alopecia areata.
4 citations
,
March 2022 in “Pharmaceutics” This review explores regenerative treatment options for non-scarring alopecia, with a focus on the potential of mesenchymal stem cells for hair regrowth, but it reports no new clinical results.
4 citations
,
March 2019 in “IP Indian Journal of Clinical and Experimental Dermatology” This study observed an association between body iron levels and non-scarring diffuse hair loss in non-menopausal women.
3 citations
,
October 2024 in “Archives of Dermatological Research” Salivary vitamin D and IL-6 could help diagnose and manage non-scarring alopecia.
3 citations
,
August 2023 in “Archives of Dermatological Research” This study suggests that wearing the hijab may lead to an earlier onset of alopecia in women, with vitamin D deficiency and seborrheic dermatitis contributing to the risk of developing telogen effluvium.
3 citations
,
December 2022 in “Rheumatology Advances in Practice” This case study reported that systemic lupus erythematosus (SLE) can initially present as patchy non-scarring alopecia, potentially misdiagnosed as alopecia areata, highlighting the importance of thorough examination.
3 citations
,
January 2017 in “Journal of Pakistan Association of Dermatology” This study found a significant association between low serum ferritin levels and nonscarring alopecia in women, suggesting the importance of addressing iron deficiency for treatment effectiveness.
3 citations
,
April 2010 in “The American Journal of Dermatopathology” This study observed similar D2-40 expression in scarring and nonscarring alopecia, with some increase in scarring cases, suggesting possible Fos-dependent mechanisms, though more research is needed for definitive conclusions.
2 citations
,
January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study on Iranian patients with non-scarring alopecia, researchers found that androgenetic alopecia was the most common subtype, with perifollicular inflammation observed more in males. They reported that transverse sectioning is generally sufficient for diagnosis, but combining with vertical sectioning provides more comprehensive information.
1 citations
,
November 2025 in “Clinical Cosmetic and Investigational Dermatology” This Mendelian randomization study suggests possible bidirectional causal links between alopecia and sleep characteristics, but findings require cautious interpretation due to multiple testing, highlighting the need for further research to explore underlying mechanisms and broader applicability.
1 citations
,
February 2019 in “PubMed” This source reports that topical minoxidil effectively treats hair loss in androgenetic alopecia, varying efficacy by ethnic groups, and when combined with other therapies, shows increased effectiveness for conditions like alopecia areata and congenital hair disorders.
1 citations
,
January 2019 in “Via Medica Journals” This case report describes the diagnosis and treatment challenges of Graham-Little syndrome, a rare condition involving cicatricial alopecia on the scalp, non-scarring hair loss in certain areas, and keratosis pilaris-like eruptions.
1 citations
,
October 2017 JAK inhibitors are effective for hair regrowth in severe alopecia areata.
1 citations
,
December 2016 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” This study reported that 80% of patients with non-scarring alopecia showed a clinical cure after treatment with unactivated platelet leukocyte autoplasma.
July 2026 in “Journal of the American Academy of Dermatology” GLP-1 and GLP-1/GIP agonists may increase the risk of hair loss.
June 2026 in “Research Square” This study found that lower vitamin D levels were inversely associated with the severity of female pattern hair loss and patchy alopecia areata, but not with telogen effluvium.