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The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

New treatments for PCOS focus on managing symptoms and improving fertility.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.

Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

Polycomb Repressive Complex 2 is not needed for hair regeneration.

Men who start balding at age 20 may have a higher chance of getting aggressive prostate cancer.

Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.

Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.

Gene mutations can cause problems in male genital development.

Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.