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Innovative methods are reducing animal testing and improving biomedical research.

In this study, peptide-based nanoparticles were successfully used to deliver the CRISPR-Cas9 system into cancer cells, effectively targeting and editing KRAS mutations, suggesting promising therapeutic potential for cancer treatment.

Home photobiomodulation therapy can improve life quality and mobility for disabled individuals.

This study found that down and guard hairs of Inner Mongolia Cashmere Goats have distinct protein compositions and physical properties, with keratin-related proteins potentially influencing these differences.

This study found that vimentin is essential for proper wound healing and cell growth by influencing EMT signaling and mTOR activity in mice.

COVID-19 can cause different types of hair loss, with telogen effluvium being the most common.

This review examines the role of certain proteins in the pathogenesis of polycystic ovary syndrome and reports no new results, emphasizing the potential for future diagnostic and therapeutic advancements.

This study found that 660 nm laser treatment and povidone iodine both eradicated Pseudomonas aeruginosa infection in mice wounds, with the laser enhancing healing, and the combination provided additive or synergistic healing benefits.

This study found that Sol/ASC-DP nanoparticles could enhance the skin permeability of minoxidil due to improved stability and hydrophobic interactions in the nanoparticle structure.

This study found that a combination of photoprotector and nighttime formulations with essential oils improved skin barrier function and structural characteristics in young men's oily, acne-prone, and photoaged skin.

This review discusses the uses of Achillea millefoilum described by Ibn Rushd, finding scientific support for its applications in treating alopecia and skin disorders.

This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.

This study found significant variability among NASPAG members in diagnostic approaches for PCOS, though there was more agreement on recommended first-line therapies such as oral contraceptives and lifestyle changes.

This study found that BMI was the only significant predictor of elevated androgen levels in adolescents with PCOS, and hyperandrogenemia was not linked to a specific PCOS phenotype.

This review discusses the application of low-level light therapy for hair loss treatment, particularly androgenetic alopecia, and reports no new clinical results; the authors suggest consideration of light source characteristics and potential pros and cons.

Low-Level Laser Therapy can stimulate healing and cell function, potentially leading to wider medical use.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

This study formulated and evaluated a polyherbal anti-dandruff shampoo, demonstrating it had good cleansing properties, antimicrobial activity against dandruff-causing microbes, and remained physically stable, potentially offering a safe and effective herbal alternative for dandruff management.

This review summarizes recent findings on the role of lactylation, a novel post-translational modification, in skin diseases, suggesting its potential as a therapeutic target by linking metabolism, epigenetic regulation, and inflammatory processes.

This review discusses current treatment strategies for alopecia and highlights the potential of lipid-based nanoparticles to improve drug delivery to the scalp and hair follicles, noting their ability to enhance skin penetration and drug stability while outlining associated challenges and the need for further research.

This study reviewed trichoscopic images to assess hair loss, finding that ayurvedic signs (lakshanas) aligned with modern trichoscopic parameters, potentially aiding accurate diagnosis and management of hair conditions.

In this study, researchers investigated the alignment of trichoscopic findings with ayurvedic signs (lakshanas) for diagnosing hair loss, suggesting that integrating these perspectives could enhance diagnostics and management of hair and scalp conditions.

In this study, the Orbis PAXMAN® scalp cooling system showed effectiveness and good tolerability in preventing chemotherapy-induced hair loss in breast cancer patients, particularly those receiving anthracycline-free chemotherapy, though the presence of comorbidities was linked to a higher risk of severe alopecia.

In this narrative review, the authors highlighted that AI-supported electronic health record analysis could help recognize Polycystic Ovary Syndrome/Polyendocrine Metabolic Ovarian Syndrome earlier, but also warned that these systems might perpetuate historical biases if not properly validated and interpreted.

In this study, researchers optimized fast-dissolving tablets of nifedipine using a systematic approach, resulting in formulations that demonstrated rapid disintegration, enhanced dissolution profiles, and improved solubility, potentially improving oral delivery for patients requiring poorly soluble antihypertensive medication.

This case study suggests that palash basti, a form of Ayurvedic treatment, may effectively manage polyendocrine metabolic ovarian syndrome by improving menstrual regularity and hormonal balance, though further studies are needed.

This study developed EGCG-loaded nanohydrogels using ethyl cellulose and polyvinyl alcohol to enhance the stability and delivery of the hydrophilic drug in aloe vera gel, optimizing encapsulation efficiency and drug release properties.

In this study, researchers suggest that hair follicle miniaturization in conditions like androgenetic alopecia may result from impaired conversion of quiescent stem cells to progenitor cells, influenced by the follicular niche, its collagen network, and various mechanical constraints.

This review concluded that polyherbal hair oils, using key medicinal plants, may offer a validated and sustainable alternative to synthetic cosmetics for hair and scalp health, with potential for industrial standardization and clinical use.

In this study, the combination of scalp cooling therapy and a scalp lotion containing DHL-HisZnNa demonstrated a 91.3% hair recovery rate among breast cancer patients undergoing certain chemotherapy regimens, with no serious adverse events reported.