67 citations
,
January 2007 in “Environmental health perspectives” This case report highlights that a woman experienced arsenic toxicosis from kelp supplements, manifesting as alopecia and memory loss, which resolved after stopping the supplements.
44 citations
,
April 2015 in “PubMed” This study reports that clinical trials of finasteride for androgenic alopecia provide insufficient and systematically biased safety data, with most participants unrepresentative of those in pivotal trials that led to FDA approval.
28 citations
,
February 2008 in “PubMed” This study found that low iron stores are a risk factor for excessive hair loss in non-menopausal women.
24 citations
,
July 2011 in “PubMed” This review discusses the classic skin characteristics of hypothyroidism, notably generalized myxedema caused by increased glycosaminoglycan deposition, and reports no clinical results.
22 citations
,
May 2016 in “Breast cancer research and treatment” This study reported cold thermal injuries on the scalp in four patients using cold caps to prevent chemotherapy-induced alopecia, suggesting improper application can lead to adverse events.
20 citations
,
December 2008 in “PubMed” In this study, treatment with finasteride 1 mg/day for five years significantly reduced the likelihood of further visible hair loss in men with androgenetic alopecia compared to placebo.
12 citations
,
January 2010 in “PubMed” This article summarizes the MHRA report on finasteride and does not present new clinical findings.
This abstract discusses pellagra as a nutritional disorder characterized by a known set of symptoms but reports no new clinical findings; the authors review existing knowledge and suggest further research.
December 2024 in “Archiv Euromedica” In this review, researchers reported that PCOS remains a complex condition with ongoing diagnostic and therapeutic challenges, highlighting recent innovations in diagnosis and treatment that provide alternative options for cases unresponsive to standard care.
89 citations
,
March 1990 in “PubMed” This study found that shaving was the most helpful and commonly used temporary hair removal method among women with facial hirsutism.
11 citations
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February 1990 in “PubMed” This study found that zinc treatment in alopecia areata patients may increase CD8+ cells, suggesting its effectiveness could be due to immunomodulation.
6 citations
,
December 1990 in “PubMed” This study examined the expression patterns of various cytokeratins in the outer root sheath of human anagen hair follicles, noting distinct differentiation patterns and localization of keratin markers.
3 citations
,
July 1990 in “PubMed” This study demonstrated that plucked human hair follicles cultured in a collagen gel matrix developed spike-like structures, suggesting a useful method to study outer root sheath cell growth and differentiation in vitro.
2 citations
,
October 1990 in “PubMed” This study suggests that autoimmune dysregulation involving HLA-DR+ T and NK cell subsets may contribute to severe patchy alopecia areata and alopecia universalis, with normalization seen after betamethasone treatment.
1 citations
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June 1990 in “PubMed” This study in Chinese patients with male pattern baldness found that 2% minoxidil solution led to moderate hair growth in 22% of participants and was generally well-tolerated.
This study found that hair germ and epidermal basal cells differ in keratin expressions in rat hair tissues, with hair-specific keratins appearing after the differentiation of each layer.
1 citations
,
April 1990 in “PubMed” This review discusses alopecia areata, including its associations, challenges in treatment assessment, and various therapies tried, without reporting new clinical results.
December 1990 in “PubMed” This article discusses the role of androgens in causing hirsutism and male pattern baldness in women and emphasizes the need for antiandrogen treatment to manage these conditions, without reporting new clinical results.
23 citations
,
December 1990 in “PubMed” This case study suggests that systemic lupus erythematosus should be considered as a potential diagnosis for immune-mediated skin disease in horses, based on multisystemic signs and specific histopathologic and immunopathologic findings.
This study evaluated local treatment with minoxidil 2% watery solution in patients with androgenetic alopecia but did not report detailed clinical outcomes.
8 citations
,
April 1990 in “PubMed” This study suggests that high concentrations of minoxidil may prolong the proliferative capacity of keratinocytes, which may partially explain its positive effect on hair growth.
1 citations
,
July 1990 in “PubMed” This case report describes a patient with eosinophilia-myalgia syndrome related to L-tryptophan use, detailing the specific symptoms and laboratory abnormalities observed.
44 citations
,
August 1990 in “PubMed” This study provides evidence for K1 and K10 derivatives' presence in the inner root sheath and hair cuticle, suggesting that these hair follicle parts may follow familiar keratinization principles.
35 citations
,
January 1990 in “PubMed” This study found that oral cyclosporin A increased hair growth in nude mice, while minoxidil did not have the same effect.
24 citations
,
September 1997 in “PubMed” This study concludes that loose anagen hair can develop in adulthood and may be difficult to distinguish from telogen hair loss, with pathologic findings offering limited diagnostic insights.
2 citations
,
February 1990 in “PubMed” In this study, 1,25-dihydroxyvitamin D3 inhibited growth and promoted differentiation in normal hair follicle cells but did not affect cells from a patient with vitamin D-dependent rickets type II, assisting in potential rapid diagnosis of the condition.
1 citations
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January 1972 in “PubMed” February 1990 in “PubMed” This study observed that hirsute females displayed increased S-phase hair bulb cells and decreased G0/1-phase cells compared to healthy females, with a strong correlation between S-phase percentages and DHEA-S levels.
February 1990 in “PubMed” This study suggests that human hair follicle cells and epidermal keratinocytes differ in their degree of keratinization and other characteristics when cultured on mixed collagen membranes.