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Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Androgens can help prevent memory problems caused by apoE4.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

CDP is crucial for lung and hair follicle cell development.

Blocking JAK-STAT signaling can lead to hair growth.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Minoxidil boosts hair growth by increasing cell production and survival.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Cathepsin L is essential for normal hair growth and development.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Minoxidil shortens baldness from chemotherapy by 50.2 days without significant side effects.