151 citations
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December 2004 in “Annals of the New York Academy of Sciences” This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
September 2025 in “Animals” This study analyzed circular RNA expression in the developing skin of foetal Gansu Alpine fine-wool sheep, identifying key circRNAs potentially involved in secondary follicle development through regulatory networks, providing insights for wool trait improvement.
39 citations
,
August 1998 in “FEBS Letters” In this study, researchers identified two novel peptidylarginine deiminases from treated rat keratinocytes, both showing enzyme activity with PAD‐R11 reflecting a characteristic of epidermal enzymes.
128 citations
,
October 2011 in “Development” This study found that adult mouse dermis can be reprogrammed by epidermal cues to resemble neonatal dermis, with changes in fibroblast proliferation and extracellular matrix composition.
9 citations
,
May 2015 in “Cardiology Clinics” This review discusses the timing and management of dyslipidemia screening around pregnancy and emphasizes dietary, exercise, and glycemic interventions during pregnancy without reporting new clinical outcomes.
3 citations
,
February 2016 in “Endocrinology and Metabolism Clinics of North America” This review discusses the timing and management of dyslipidemia screening and intervention in pregnancy and highlights the need for lipid profile assessments each trimester; it reports no clinical results.
May 2017 in “American Society of Health-System Pharmacists eBooks” This abstract provides definitions and descriptions of various medical and scientific terms but reports no new research findings.
23 citations
,
August 2005 in “Expert opinion on pharmacotherapy” This review examines the benefits and potential risks of androgen replacement therapy for male hypogonadism but reports no new clinical results; the authors highlight the need for careful risk assessment, especially in older men.
1 citations
,
July 2012 in “British Journal of Dermatology” This synopsis reviews key dermatological advancements discussed at the British Association of Dermatologists meeting in 2011 and reports no new clinical results.
June 2020 in “Journal of Investigative Dermatology” This study observed that human primary adult hair matrix keratinocytes may have the potential to generate hair follicle organoids, suggesting possible applications in hair follicle neogenesis and preclinical hair growth agent screening.
August 2018 in “Journal of The American Academy of Dermatology” Older men's scalp damage increases with age and sun exposure, a baby girl in the Philippines has Schimmelpenning syndrome, and thyroid screening is advised for children with hair loss and certain risk factors.
61 citations
,
September 2016 in “NPG Asia Materials” This study developed thermo-reversible glycol chitosan hydrogels that effectively form and maintain 3D cell spheroids within one day, offering a simplified method for creating biologically realistic cultures for tissue regeneration and drug screening applications.
56 citations
,
April 2015 in “American journal of medical genetics. Part A” This study reports on eight previously unpublished cases of Bohring-Opitz syndrome with ASXL1 mutations, suggesting the importance of screening for Wilms tumors in these patients.
44 citations
,
June 2018 in “Journal of Cellular Physiology” This study found that using 3D dermal papilla spheroid models enhances extracellular matrix production and hair follicle marker expression, providing insights into hair follicle biology and potential for drug screening.
38 citations
,
March 2020 in “Current Hypertension Reports” This review discusses how various reproductive factors are linked to increased risks of hypertension and cardiovascular disease, noting associations with impaired fetal growth, male hypogonadism, and effects of contraceptive use, but reports no new results.
30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
21 citations
,
January 2006 in “Pediatrics” This review discusses how certain genetic, infectious, and metabolic conditions might influence disease severity and highlights the potential for new therapies, but it presents no new research findings.
17 citations
,
December 2019 in “Stem Cell Research & Therapy” This study found that their system effectively supports the rapid formation of human hair follicle organoids, providing a platform for studying hair regeneration and drug screening.
4 citations
,
September 2024 in “BMC Oral Health” This review highlights the lack of evidence on dental care access and referral pathways for children with EB, emphasizing the need for dentists and multidisciplinary teams to understand EB for effective treatment; it reports no new study results.
359 citations
,
September 2017 in “European Journal of Epidemiology” This article discusses the rationale, design, and significant findings of the long-running Rotterdam Study but reports no new clinical results.
48 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This article reviews the genetic and protein interactions involved in hair growth, highlighting regulatory sequences, expression patterns, and potential genetic modifications, but presents no new experimental findings.
28 citations
,
November 2014 in “Current Diabetes Reports” This review discusses the complex links between polycystic ovary syndrome, insulin resistance, and potential metabolic risks starting in adolescence, noting the need for early screening and treatment but reports no new clinical results.
5 citations
,
November 2011 in “Expert Review of Dermatology” This review discusses the causes, diagnosis, and treatment of pediatric alopecia, emphasizing early diagnosis and considering holistic approaches, but reports no new clinical results.
153 citations
,
June 2015 in “GenomeBiology.com” This study found that both genome-wide screening methods identified the VTRNA2-1 epiallele as highly responsive to environmental influences, suggesting a link between early embryonic environment, epigenetic changes, and human disease.
3 citations
,
June 1997 in “Veterinary Dermatology” In this study, daily topical minoxidil treatment in neonatal hairless pups led to increased hair growth and the development of hair follicles in the treated areas.
6 citations
,
August 2024 in “Biomacromolecules” This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.
4 citations
,
February 2023 in “Stem Cell Research & Therapy” This study found that papillary dermal fibroblast progenitors in newborn mouse skin can be isolated and cultured to generate male germline cell precursors, demonstrating their potential through differentiation into cells with meiotic capability.
60 citations
,
December 2005 in “Biomedical Papers” This article reviews hair analysis for drug detection and its applications in various fields, but reports no new research findings, emphasizing the need to consider the method's complexities and potential pitfalls.
34 citations
,
June 2022 in “Viruses” This study found that the natural alkaloid cepharanthine effectively inhibited porcine epidemic diarrhea virus infection in newborn piglets.
7 citations
,
November 2006 in “Pediatric Dermatology” This article describes the first reported case of alopecia in a neonate with congenital syphilis.