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Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Fat cells in the skin help start healing and form important repair cells after injury.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Fullerenes show potential in skin care but need more safety research.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Mutant mice help researchers understand hair growth and related genetic factors.