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The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.

Finasteride may help reduce tic severity in male Tourette syndrome patients.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

Finasteride helps treat hair loss by blocking enzyme activity.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

FGF21 can help reduce skin inflammation caused by C. acnes.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Activin A increases inner ear hair cell development, while follistatin decreases it.

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Activating TRPA1 reduces scarring and promotes tissue regeneration.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.