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The Li-Pa/Ca and Do/Ca chemotherapy regimens for serous ovarian cancer showed better short-term and long-term results than the Pa/Ca regimen.

Leflunomide is effective for rheumatoid arthritis but has significant side effects.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Topical minoxidil may not improve the appearance of balding men, according to a letter in this document.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Androgens can help prevent memory problems caused by apoE4.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Hair loss causes stress and affects mental health; treatment and support needed.

Latanoprost can make eyelashes longer, thicker, and darker.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.