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Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride may cause slight depression and anxiety.

Estrogen helps prevent artery plaque by stopping monocyte capture in blood vessels.

A woman's shingles infection triggered her first episode of a rare neurological disorder and blood vessel inflammation.

Vitiligo is a skin condition causing white patches, likely due to an autoimmune issue.

Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.

Many people with hair loss experience scalp pain known as trichodynia, but the causes are unclear and treatments vary.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Finasteride reduces new brain cells in male mice, possibly causing depression.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Gut flora changes could potentially indicate depression, but more research is needed.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Early NAS level changes affect alcohol consumption vulnerability.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.

Etifoxine, an anxiety drug, can lessen brain inflammation and cognitive issues in mice, partly by increasing production of protective brain steroids.