171 citations,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
165 citations,
December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
89 citations,
February 1993 in “Journal of Medicinal Chemistry” New compounds called benzoquinolinones may treat conditions linked to excess DHT.
49 citations,
January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.
23 citations,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
21 citations,
August 1994 in “Clinical endocrinology” 5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
16 citations,
October 2007 in “Andrologia” DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
10 citations,
October 1992 in “Hormone and Metabolic Research” Finasteride safely lowers DHT levels without affecting hormone levels, helping with conditions like enlarged prostate, acne, and hair loss.
8 citations,
July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
8 citations,
January 1991 in “European Urology” Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
November 2024 in “Clinical Cosmetic and Investigational Dermatology” Rosemary oil may effectively treat hair loss with fewer side effects, but more research is needed.
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
Targeting CXXC5 and GSK-3β may help treat male pattern baldness.
31 citations,
October 2017 in “Dermatologic Surgery” Hair transplants look natural, but the best method is debated, and PRP shows promise for hair regrowth.
2 citations,
June 2022 in “Phytomedicine” Shi-Bi-Man helps hair regrowth by activating the FGF pathway in cells.
June 2023 in “International journal of pharmaceutical quality assurance” Eclipta alba extract could be a promising natural treatment for hair loss.
12 citations,
August 2013 in “Facial Plastic Surgery Clinics of North America” Choose hair restoration surgery candidates carefully and plan treatments for a natural look and future hair loss.
December 2023 in “Research Square (Research Square)” 12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.
54 citations,
August 2009 in “Dermatologic Surgery” Modern hair transplants use small grafts for a natural look and drugs to prevent further loss, with high patient satisfaction.
31 citations,
July 2015 in “Clinical, Cosmetic and Investigational Dermatology” Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.
21 citations,
October 2008 in “Indian Journal of Plastic Surgery” Hair transplantation surgery has improved, giving more natural results, and success depends on a skilled team and proper technique.
11 citations,
July 2008 in “Facial Plastic Surgery Clinics of North America” Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.
4 citations,
September 2019 in “Journal of Cosmetic Dermatology” FUE megasession effectively treats severe hair loss with natural-looking results in one operation.
1 citations,
February 2004 in “Medical Hypotheses” Certain cultural hair practices might cause baldness by affecting natural hair oils and stem cell delivery to hair follicles.
32 citations,
November 2012 in “Aesthetic Surgery Journal” Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.
7 citations,
September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.
Hair transplants are effective for male and female pattern baldness, have evolved in technique, and require careful planning for natural results and managing complications.
September 2017 in “Springer eBooks” Older East and Southeast Asian men need less hair density for hair restoration satisfaction, and natural hairline features should guide surgery plans.
13 citations,
September 2015 in “Aesthetic Surgery Journal” Transplanting hair from the nape and around the ear to the hairline and temples generally satisfies patients and looks natural.
5 citations,
March 2018 in “Dermatologic Surgery” The study found that most donor sites are good for hairline restoration in Southeast Asian women, but hair characteristics should match for a natural look, and aging can reduce hair density and diameter.