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Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Some birth control pills have a higher risk of blood clots than others.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.

Pregnancy can change skin disease severity, with some conditions improving and others worsening, and treatment should balance benefits and fetal safety.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

COVID-19 can cause skin issues like chilblains and rashes, which may help in early detection, especially in patients without other symptoms.

Spermidine helps protect against aging by preserving telomere length.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.

Non-immune factors play a significant role in alopecia areata.

Some children who had stem cell transplants developed permanent hair loss, especially when treated with a drug called busulphan.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.

Women with Systemic Lupus Erythematosus should have closely monitored pregnancies and avoid certain medications to improve their pregnancy outcomes.

Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

Sodium selenate was found to be safe and possibly slows Alzheimer's progression, but more research is needed.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

People with hidradenitis suppurativa have a higher risk of heart attacks and strokes.

Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

Dutasteride and finasteride have similar risk for osteoporosis and fractures in older men.