This review highlights that nanotechnology offers promising avenues for enhancing drug delivery and developing new therapeutic strategies for androgenetic alopecia, though challenges remain in clinical translation and the need for long-term safety studies.
January 2023 in “International Journal of Pharmaceutical Research and Development” This review discusses alopecia, its pathophysiology, nanotechnology-based drug delivery systems, and related quality of life issues, without reporting new clinical results.
This review critically analyzes recent literature on the use of nanotechnology in alopecia treatment, reporting promising results for improving drug delivery and hair growth, though challenges in maintaining physical stability may limit large-scale commercialization.
November 2022 in “IntechOpen eBooks” This review discusses nanoparticle-based wound-healing materials, detailing their benefits, limitations, and recent advancements, and emphasizes the need for further understanding to enhance therapeutic outcomes.
117 citations
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August 2005 in “Ultramicroscopy” This study systematically characterized the nanomechanical properties of human hair, such as hardness and elastic modulus, across different ethnicities and treatment conditions using nanoindentation and scanning electron microscopy.
March 2026 in “Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials” In this study, researchers found that hair fibers exposed to bleaching and UV irradiation displayed significantly more damage, including increased adhesion and surface heterogeneity, compared to untreated hair, highlighting a synergistic degradation pathway affecting the hair cuticle's integrity.
8 citations
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January 2019 in “Nanomedicine” This commentary reviews the application of pharmaceutical nanotechnology in Egypt, highlighting promising developments and diverse drug-delivery approaches, but reports no new research findings.
5 citations
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July 2025 in “Nutrients” This study reviews how advancements in nanotechnology have improved food safety, nutrition delivery, and health interventions, but it also highlights the need for more research into safety evaluations and regulatory concerns.
December 2023 in “̒Ulūm-i dārūyī” This review provides a comprehensive examination of the causes and treatments for hirsutism in women, highlighting the role of pharmacological therapies and novel nanotechnology-based methods in improving patient quality of life.
December 2013 in “Biomedical and biopharmaceutical research” This review discusses technological advances in liposome systems for drug delivery and reports no new clinical results; it highlights the clinical acceptance and market presence of liposomal products.
30 citations
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April 2023 in “Indian Journal of Ophthalmology” This review examines various new approaches for treating dry eye disease, including biomaterials, regenerative therapy, and tissue engineering, and emphasizes the need for clinical efficacy studies to advance these therapies for human use.
January 2019 in “Research & Reviews: Journal of Pharmaceutics and Nanotechnology” This review discusses polycystic ovary syndrome's metabolic and reproductive impacts, highlighting its insulin resistance and related complications, but reports no new research findings, underscoring the need for lifestyle modifications.
19 citations
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July 2018 in “ACS biomaterials science & engineering” This study showed that chemical and mechanical treatments significantly alter the nanoscale surface properties of hair, affecting its roughness, mechanical stiffness, adhesion, and surface potential.
353 citations
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May 2016 in “TrAC Trends in Analytical Chemistry” This review discusses recent advances in droplet microfluidics for chip-based technologies such as single-cell analysis, small-scale cell cultures, and high-throughput drug screening, and it reports no new results.
January 2026 in “Journal of advanced Biomedical and Pharmaceutical Sciences” This review highlights niosomal cetirizine as a promising strategy for managing alopecia, potentially enhancing local bioavailability and reducing systemic exposure.
This study suggests that bioactives like Curcumin, Quercetin, and "Tulsi" may relieve chemotherapy-induced adverse drug reactions in cancer patients, potentially reducing resistance and recurrence.
466 citations
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June 2009 in “Experimental dermatology” This review discusses recent advances in understanding acne pathobiology, highlighting the potential for developing new customized therapies, but it reports no new clinical findings.
122 citations
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December 2022 in “International Journal of Molecular Sciences” In this review, researchers discussed recent advances in nanotechnology for topical skin applications, highlighting how nanocarriers enhance skin penetration and targeting in treatments for diseases like melanoma and psoriasis, while acknowledging that the penetration mechanisms and health impacts of nanoparticles remain not fully understood.
89 citations
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January 2021 in “Molecules” This review discusses the applications of biopolymeric composites in controlled drug release, tissue engineering, and wound healing, but reports no new experimental results, highlighting the need for further development and analysis.
79 citations
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December 2017 in “Cosmetics” This review study focused on various in vitro methods to evaluate skin permeation and retention of sunscreens, highlighting the importance of assessing sunscreen penetration due to widespread nanomaterial usage and advancements in cosmetic formulation.
43 citations
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July 2019 in “Stem Cells International” This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.
42 citations
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November 2022 in “Cosmetics” This review concluded that using niosomes in cosmetics significantly enhances the aesthetic and therapeutic effects of skin and hair products, potentially aiding in treating skin conditions.
41 citations
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September 2021 in “Materials” This review discusses the role of biomaterials and colloidal drug delivery systems in promoting tissue regeneration within regenerative medicine, but it reports no new clinical results.
40 citations
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January 2016 in “Elsevier eBooks” This article explains the structure and multifunctional roles of the human skin, including its protective, regulatory, and sensory functions, but does not report new research findings.
34 citations
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January 2020 in “Expert opinion on drug delivery” This review discusses various novel drug delivery approaches to enhance scalp drug penetration for alopecia treatment but reports no new clinical results.
28 citations
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February 2016 in “International Journal of Nanomedicine” This study found that freeze-dried finasteride nanoparticles improved the stability, solubility, and in vitro dissolution of the drug, indicating potential benefits for poorly water-soluble drugs.
27 citations
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September 2018 in “Nanomedicine: Nanotechnology, Biology and Medicine” This review discusses recent advances in hair regeneration therapies, highlighting the potential of nanotechnology and pluripotent stem cells, and reports no new results, emphasizing the need for further research.
25 citations
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February 2024 in “Pharmaceutics” This article outlines how nanotechnology strategies, including phospholipid-based nanocarriers like liposomes, could enhance the effectiveness and skin tolerability of acne treatments, aiming to reduce side effects and improve patient compliance in managing acne vulgaris.
20 citations
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January 2022 in “REVIEWS ON ADVANCED MATERIALS SCIENCE” This review explores how nanoparticles enhance cosmeceutical formulations, analyzing their roles in transporting active ingredients, and highlights the progress and challenges in using nanotechnology for beauty and health products.
20 citations
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August 2014 in “Therapeutic delivery” This article reviews potential applications and challenges of using the transfollicular route for drug delivery but does not present new clinical findings; it calls for further exploration and development in this field.