156 citations
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January 1989 in “Genes & Development” This study found that keratin K14 expression occurs early in epidermal cell differentiation, while a hair-specific keratin is expressed later in hair matrix cells, suggesting developmental divergence between the two cell types.
4 citations
,
January 2021 in “Dermatologic Therapy” This review highlights current and future AI applications in hair restoration and diagnosis of hair disorders, including automated systems for hair detection and self-diagnosis, emphasizing the need for experts to understand their benefits and limitations.
57 citations
,
February 2018 in “Journal of the American Academy of Dermatology” This review critiques the unwarranted promotion of biotin for hair and nail improvements, noting the lack of evidence for routine use and highlighting concerning trends in consumer and physician practices.
August 2023 in “JOJ dermatology & cosmetics” This literature review found that antibiotics are a major cause of cutaneous adverse drug reactions, which represent up to 60% of all adverse drug reactions, and emphasized the need for clinicians to better understand and manage these reactions.
December 2021 in “Turkderm” This research aims to evaluate the impact of the COVID-19 post-crisis period and normalization process on dermatology practice, suggesting implications for future healthcare challenges; no new results are reported.
December 2004 in “Medicine” This article outlines a detailed framework for taking dermatological history and examination, emphasizing the importance of considering various factors like medication and occupational history; it reports no new clinical findings.
37 citations
,
March 1990 in “The Journal of Pediatrics” Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
67 citations
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September 2003 in “Journal of cutaneous pathology” This review discusses the various skin manifestations associated with end-stage renal disease and their potential causes but reports no new clinical findings; the authors emphasize pruritus as a significant condition.
27 citations
,
July 2015 in “International Journal of Dermatology” This study found that skin disorders are prevalent among elderly individuals and are often associated with underlying systemic diseases.
6 citations
,
April 2024 in “Health Science Reports” This study found that young patients with severe AA are more prone to nail abnormalities such as pitting and leukonychia, with koilonychia and red spots lunula in more severe cases.
1 citations
,
January 2013 in “Springer eBooks” The document concludes that skin and nail changes can indicate various underlying health conditions.
29 citations
,
August 2011 in “PubMed” This study describes how shotgun proteomics can identify over 300 proteins in hair shafts, potentially allowing for the diagnosis of diseases through noninvasive human proteome sampling.
10 citations
,
January 2021 in “BioMed Research International” This study found that patients who recovered from COVID-19 experienced various skin, hair, and nail issues, with hair shedding being more common in those with moderate to severe cases.
187 citations
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May 1988 in “Differentiation” This study found that trichocytic cytokeratins, typically found in hair, are also present in nails, filiform papillae of the tongue, and the epithelial reticulum of the thymus.
64 citations
,
June 1992 in “International Journal of Dermatology” Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
61 citations
,
October 2010 in “Postgraduate Medical Journal” This study found that dermatological issues, such as xerosis and pigmentation, are common in chronic kidney disease patients and increase with the severity and duration of the disease, indicating that dialysis often exacerbates these conditions.
53 citations
,
September 2017 in “BMJ Open” This study observed that nearly all aged nursing home residents in Berlin had at least one dermatological condition, with xerosis cutis being the most common, but few associations with demographics or medical characteristics were found.
18 citations
,
August 2018 in “The FASEB journal” This study found that Hoxc13-/- rabbits exhibit complete hair loss on the head and dorsum, providing a potential model for understanding human ECTD-9 and related dermatological conditions.
17 citations
,
February 2012 in “Cutaneous and Ocular Toxicology” This study found that xerosis and pruritus are prevalent in patients with chronic renal failure undergoing hemodialysis, highlighting the importance of early recognition of skin issues to alleviate discomfort and reduce complications.
March 2026 in “FMDB Transactions on Sustainable Health Science Letters” This study developed a method using Convolutional Neural Networks to detect nutritional deficiencies, such as iron, zinc, biotin, and vitamins, through high-resolution images of hair and nails, achieving an 89% accuracy rate in identifying these deficiencies.
March 2025 in “Dermatology” Systemic therapies improve nail psoriasis but have high side effects; more research is needed.
July 2024 in “Nursing Research” This study highlights the use of hair and fingernail cortisol levels as retrospective indicators of chronic stress, particularly in minoritized populations facing social stressors that increase the risk of mental health issues.
March 2024 in “IP Indian journal of clinical and experimental dermatology” In this study conducted at a tertiary care center, rural elderly patients often exhibited skin conditions like wrinkling, generalized pruritus, xerosis, eczematous skin conditions, and psoriasis, highlighting the need for better health education on skin care, early diagnosis, and management.
October 2021 in “Dermatology Reports” This study found that serum IL-17A levels were significantly higher in patients with alopecia areata compared to healthy controls and correlated with disease severity and activity.
December 2010 in “Bariatric Nursing and Surgical Patient Care” This article provides a clinical Q&A on bariatric nursing and surgical patient care and reports no new research findings.
January 2003 in “Steinkopff eBooks” This review discusses the incidence, demographics, and associated conditions of alopecia areata and provides no new clinical findings.
18 citations
,
July 2008 in “Current Oncology Reports” EGFR cancer drugs often cause a rash, which can lead to distress and isolation, but may also improve outcomes for some cancer patients. Current treatments for the rash are limited, but a compound called menadione shows promise.
1 citations
,
August 2023 in “Journal of cosmetic dermatology (Print)” This review discusses the potential link between selenium supplementation and symptoms of chronic selenium toxicity, such as hair loss and nail dystrophy, due to excess intake leading to disruptions in hair and nail protein structure.
1 citations
,
November 2011 in “Archives of Dermatology” A woman's hair loss was caused by her husband's testosterone gel and a diabetic man's nail disease led to bone infection, both treated successfully.
1 citations
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January 2013 in “Elsevier eBooks” The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.