research Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Finasteride effectively blocks enzyme causing male pattern baldness.
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research Scalp Reduction Revisited: A 10-Year Experience
Scalp reduction surgery is safe and effective for certain patients with hair loss, leading to dense hair coverage and high satisfaction.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Investigation of the Damage on the Outermost Hair Surface Using ToF-SIMS and XPS
Bleaching hair causes significant damage by breaking down proteins and fatty acids.
research Investigation by Imaging Mass Spectrometry of Biomarker Candidates for Aging in the Hair Cortex
Certain molecules in hair change with age and could be used for cosmetic treatments.
research Geranylated Coumarins From Thai Medicinal Plant Mammea Siamensis With Testosterone 5α-Reductase Inhibitory Activity
Compounds from the plant Mammea siamensis may help treat hair loss.
research Biocompatibility Of Kaps-Depleted Residual Hair
KAP-depleted hair causes less immune response and is more biocompatible for implants.
research Evaluating the Antioxidant Effects of Human Hair Protein Extracts
Human hair protein extracts can protect skin cells from oxidative stress.
research Quintaquinone, a Merosesquiterpene from the Yellow Sponge Verongula cf. Rigida
A new compound from a sponge strongly inhibits an enzyme linked to male-pattern hair loss without being toxic at low levels.
research Mycobacteriosis in a Pet Ferret (Mustela putorius furo) Caused by Mycobacterium Xenopi: A Case Report on Neglected Risk of Zoonotic Transmission
A pet ferret had a serious infection from Mycobacterium xenopi, which can spread to humans.
research Unraveling Childhood Tinea Capitis: A Multi-Dimensional Investigation Using Dermoscopy, Scanning Electron Microscopy, and Mass Spectrometry
Tinea capitis in a child was caused by a fungus from cats, highlighting the need for accurate diagnosis and treatment.
research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
Method detects finasteride in plasma at very low concentrations.
research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration
Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
research Contact Cooling of the Skin
Skin can be cooled quickly and safely during laser treatments to protect it without affecting deeper layers.
research Neuroactive Steroid Levels and Psychiatric and Andrological Features in Post-Finasteride Patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research Decreased Androgen Receptor Gene Methylation in Premature Pubarche: A Novel Pathogenetic Mechanism?
Reduced AR gene methylation may cause early pubic hair growth in girls.
research Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry
Method detects finasteride in plasma and semen with high sensitivity and accuracy.
research Iontophoresis of Minoxidil Sulphate Loaded Microparticles: A Strategy for Follicular Drug Targeting?
Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.
research Copy Number Variation Regions in Nellore Cattle: Evidence of Environmental Adaptation
Nellore cattle have genetic variations linked to their adaptation to tropical environments.
research Intracrine Testosterone Activation in Human Pancreatic Beta-Cells Stimulates Insulin Secretion
Testosterone helps human pancreatic cells increase insulin release.
research FeCl3-Catalyzed C-N Coupling Reaction Between Cyclic Ethers and Heterocyclic Amines
Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.
research Bio-Monitoring of Air Quality Using Leaves of Trees and Lichens in Urban Environments
Tree leaves and lichens can effectively indicate air pollution levels in cities.
research Wound Microbiota and Its Impact on Wound Healing
Wound healing is greatly affected by the types of bacteria present, which can either help or hinder the process.
research CXCL12 Neutralizing Antibody Promotes Hair Growth in Androgenic Alopecia and Alopecia Areata
Blocking the protein CXCL12 with a specific antibody can increase hair growth in common hair loss conditions.
research Hydrobiome Of Thermal Waters: Potential Use In Dermocosmetics
Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.
research Structures of Get3D Reveal a Distinct Architecture Associated with the Emergence of Photosynthesis
Get3d protein helps maintain photosynthesis in plants and photosynthetic bacteria.
research Medicinal Plants Use for Home Remedies in Sri Lanka: A Review
The document concludes that in Sri Lanka, 25 common plants are traditionally used as home remedies for various health issues due to their medicinal properties.
research Chemical Examination of Three Indian Medicinal Plants and Their Hair Growth Evaluation Studies
Three Indian medicinal plant compounds help hair growth.
research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.