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The intensive conventional diet with exercise led to better long-term weight loss and health improvements than the very low calorie diet in obese type 2 diabetics.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Wound healing insights can improve regenerative medicine.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Minoxidil improves blood flow in heart failure patients.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Young Czech women with PCOS have a higher risk of heart problems and should be regularly checked for cholesterol and glucose issues.

Apoptosis is crucial for healthy skin and treating skin diseases.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Minoxidil use in children may cause heart issues.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Jaw wiring helps with weight loss but long-term habits are needed to keep it off.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.