4 citations
,
July 2012 in “Genesis” This study reported that a Megsin-Cre transgene enables genetic manipulation primarily in skin, forestomach, and esophagus tissues, offering a new tool for studying development and diseases in these areas.
49 citations
,
June 2019 in “eLife” This study reported the discovery of large-scale haplotypes (cenhaps) in human centromere regions, revealing deep genetic diversity, including introgressed Neanderthal and ancient African lineages.
41 citations
,
October 2019 in “Biomolecules” This review highlights the role of all-trans retinoic acid in regulating stem and progenitor cell proliferation and differentiation, suggesting its potential to enhance treatments in regenerative medicine and cancer.
37 citations
,
April 2015 in “Development Growth & Differentiation” This article introduces the concept of organ size control in regeneration, regulated by the Hippo signaling pathway, but reports no new experimental results.
7 citations
,
August 2022 in “Experimental dermatology” This review discusses the role of YAP/TAZ proteins in skin cancer physiology and tumorigenesis, and the potential of targeting these proteins in skin cancer treatments, but presents no new experimental findings.
3 citations
,
October 2024 in “International Journal of Molecular Sciences” This review highlights the regenerative abilities of *Xenopus laevis*, focusing on how tadpoles regrow complex tail structures and the cellular and molecular mechanisms behind this. It underscores *X. laevis* as a valuable model for understanding regeneration, with insights potentially advancing regenerative medicine.
1 citations
,
November 2011 in “British journal of pharmacology” This abstract provides a comprehensive overview of enzyme classification, function, and interaction with drugs, but does not present new research findings.
1 citations
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September 2022 in “Journal of dermatological science” This study found that a combination of vitamins in hair care products promoted hair shaft elongation in a mouse model by activating the PlGF/VEGFR-1 signaling pathway.
February 2025 in “FASEB BioAdvances” In this study, hypoxic conditions were found to enhance stemness in hair follicle neural crest stem cells, while inhibiting the Hippo pathway significantly decreased their proliferation.
34 citations
,
August 2019 in “Journal of Allergy and Clinical Immunology” mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
3 citations
,
July 2016 in “Tropical Journal of Pharmaceutical Research” This study found that the proposed LC-MS/MS method accurately quantified the drug content in split tablets of finasteride and terbinafine, revealing significant variability and suggesting that non-scored tablets should not be split.
February 2012 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study observed nestin-GFP expressing stem cells in the hair follicle bulge of living mice using high-resolution in-vivo multiphoton tomography, allowing migration tracking within their natural skin environment.
January 2026 in “International Journal of Endocrinology” This study found that using renin-angiotensin system-targeting antihypertensive agents or statins is associated with reduced serum HER2 levels, which may influence the risk of metabolic syndrome in women.
January 2011 in “Journal of Human Genetics” This study found a severe MBTPS2 gene mutation in a Japanese IFAP syndrome patient, suggesting other factors may influence the syndrome's clinical features compared to previously studied patients.
174 citations
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November 2016 in “Cell stem cell” This study found that squamous cell carcinomas from hair follicle stem cells are more prone to epithelial to mesenchymal transition and metastasis than those from interfollicular epidermis, due to distinct chromatin landscapes.
9 citations
,
March 2018 in “European journal of dermatology/EJD. European journal of dermatology” This study in a Pakistani family identified a novel ST14 gene variant as the likely genetic cause of autosomal recessive ichthyosis with hypotrichosis syndrome.
1 citations
,
April 2022 in “Cell Death Discovery” This study found that SMAD2 overexpression in human hair follicle stem cells promoted differentiation and apoptosis while inhibiting proliferation, and Smurf2 upregulation limited mouse wound healing by suppressing the SMAD2/NANOG/DNMT1 axis.
6 citations
,
June 2025 in “Cell Reports” This study found that the IL-33/ST2 axis may protect against skin carcinogenesis by promoting cross-talk between epithelial cells and regulatory T cells to minimize mutations and contain tissue damage.
April 2023 in “Journal of Investigative Dermatology” This study found that human epidermal stem cells can adapt to small temperature variations via mTOR signaling, and that prolonged mTORC1 inhibition supports stem cell maintenance.
2 citations
,
January 2023 in “Sexual Medicine” This study found that the MTCK, a masturbation aid, significantly improved intravaginal ejaculation latency time and some related sexual function scores in men with premature ejaculation after 8 weeks of use.
January 2026 in “Figshare” This table reports gene set enrichment analysis scores for hair follicle compartments across diseases and sampling methods, providing comparisons but no new experimental findings.
11 citations
,
December 2018 in “Bone” This study found that a high-energy shock wave can increase osteogenic activities in human mesenchymal cells, offering insights into potential therapeutic targets for trauma-induced heterotopic ossification.
78 citations
,
January 2013 in “Brachytherapy” This study found that high-dose-rate electronic brachytherapy was effective for treating nonmelanoma skin cancer, with no recurrences and good to excellent cosmetic results at 1 year or more.
This study found that the transcription factor Meis2 is crucial for the maturation and innervation of sensory neurons responsible for light touch in mice, with its absence leading to reduced touch sensitivity.
September 2020 in “Acta Scientific Cancer Biology” This case report describes how personalized treatment based on Encyclopedic Tumor Analysis successfully led to durable regression in a woman with advanced pilomatrical carcinoma, unresponsive to standard care.
16 citations
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June 1992 in “PubMed” In this case report, high-dose intravenous methylprednisone followed by oral prednisolone improved painful muscle cramps in a young man unresponsive to other treatments, suggesting an autoimmune mechanism may be involved.
September 2025 in “Experimental & Molecular Medicine” This study observed that the small molecules KY19382 and KY19334 inhibited cancerous traits in human cutaneous squamous cell carcinoma cells by suppressing the Wnt/β-catenin pathway, indicating their potential as treatments for cancers involving CDK1 overexpression and diseases related to CXXC5 accumulation.
20 citations
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May 2023 in “Cancer Nanotechnology” The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.
71 citations
,
January 2011 in “Journal of cutaneous pathology” This case report describes the first confirmed instance of trichodysplasia spinulosa in a child with Down syndrome and leukemia, linking it to the TS-associated polyomavirus.
3 citations
,
February 2023 in “BMJ Case Reports” This case report describes a woman with trichotillomania who experienced marked improvement and hair regrowth after off-label onabotulinumtoxinA treatment.