research Rapid Determination of Finasteride in Human Plasma by UPLC-MS/MS and Its Application to Clinical Pharmacokinetic Study
New method measures finasteride in blood quickly and accurately.
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research Signal Transducer and Activator of Transcription 5B Deficiency Due to a Novel Missense Mutation in the Coiled-Coil Domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS
The method can measure vitamin B3 levels in human hair accurately.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research The Association Between Metabolic Syndrome Components and Hair Loss in Both Male and Female Individuals
Hair loss may signal metabolic problems and increased risk of heart disease, suggesting people with hair loss should be checked for these issues.
research Alemtuzumab-Induced Secondary Autoimmune Skin Disorders as Side Effects of Multiple Sclerosis Therapy: Problem That Can Be Influenced or Fate? A Narrative Overview of the Literature and a Neuroprotective Role of Vitamin D
Taking vitamin D might improve life for MS patients and reduce skin side effects from alemtuzumab treatment.
research Synthesis of N-Substituted 3-Oxo-17b-Carboxamide-4-Aza-5a-Androstanes and the Tautomerism of 3-Oxo-4-Aza-5-Androstenes
Researchers made two new compounds that could be used for medicine.
research Innovative Method for the Analysis of Dexpanthenol in Hair Care Products
New method quickly and accurately measures dexpanthenol in hair products.
research Androgens in Women: Critical Evaluation of Methods for Their Determination in Diagnosing Endocrine Disorders
The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.
research Liquid Chromatography-Mass Spectrometry-Based In Vitro Metabolic Profiling Reveals Altered Enzyme Expressions in Eicosanoid Metabolism
The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.
research Human Gene Correlation Analysis: A Tool for the Identification of Transcriptionally Co-Expressed Genes
The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.
research Expression and Tissue Distribution Analysis of Vimentin and Transthyretin Proteins Associated With Coat Colors in Sheep (Ovis Aries)
Vimentin and transthyretin proteins are linked to black coat color in sheep.
research The Role of Lysophosphatidic Acid in the Physiology and Pathology of the Skin
Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research Acne in Children: Presentation and Treatment Overview
Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.
research Conflicting Auxin-Phosphate Signals Impact on RSL2 Expression and ROS Homeostasis Linked to Root Hair Growth in Arabidopsis
Auxin helps root hairs grow in high phosphate by affecting ROS and involving RSL2 and RSL4.
research Extracellular Matrix Sensing by FERONIA and Leucine-Rich Repeat Extensins Controls Vacuolar Expansion During Cellular Elongation in Arabidopsis Thaliana
FERONIA and LRX proteins help control cell growth in plants by regulating vacuole expansion.
research Cheating on Forensic Hair Testing? Detection of Potential Biomarkers for Cosmetically Altered Hair Samples Using Untargeted Hair Metabolomics
Researchers found markers that can tell if hair has been bleached, which could improve hair test accuracy.
research Current Prospective in the Management of Depression Using Off-Label Drugs and Advanced Drugs
New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Baricitinib: From Rheumatoid Arthritis to COVID-19
Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
research Ongoing Concerns Regarding Finasteride for the Treatment of Male-Pattern Androgenetic Alopecia
Finasteride may cause side effects; more research needed.
research Metabolic Syndrome and Alopecia: A Case-Control Study
People with androgenetic alopecia may have a higher risk of heart problems compared to those with alopecia areata or healthy individuals.
research Prevalence of Autoimmune Diseases and Other Comorbidities in Patients With Psoriasis in the United States
People with psoriasis have more health problems, including autoimmune diseases, than those without it.
research APCDD1 Is a Novel Wnt Inhibitor Mutated in Hereditary Hypotrichosis Simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research HPLC-ESI-MSn Characterization of Phenolic Compounds, Terpenoid Saponins, and Other Minor Compounds in Bituminaria Bituminosa
Researchers found over 40 compounds in Bituminaria bituminosa, including many flavonoids and some with potential for medical and hair care uses.
research Primary Generalized Glucocorticoid Resistance And Hypersensitivity
The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
research Structural Characterization of Cyclosporin A, C, and Microbial Bio-Transformed Cyclosporin A Analog AM6 Using HPLC–ESI–Ion Trap-Mass Spectrometry
Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.
research Volatile Signaling by Sesquiterpenes from Ectomycorrhizal Fungi Reprograms Root Architecture
Fungi-produced compounds can change plant root growth.