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Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Surgery is the main treatment for liver hydatidosis, but has risks; albendazole is the most effective drug but can have side effects.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.