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This review discusses drug repurposing strategies for rare diseases, highlighting methodologies, achievements, and challenges, but reports no new clinical results.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

This study found that drug transport through artificial sebum varies depending on the compound, suggesting that sebum-targeted delivery can be optimized by selecting compounds based on their distinct transport profiles in sebum versus skin.

This study identified differentially expressed proteins and pathways potentially involved in wool bending in Zhongwei goats, with specific genes like COL6A1 and CRNN emerging as important candidates in this process.

This study identified hypericin and berberine as compounds that can support hair growth by enhancing oxytocin receptor expression and acting as an oxytocin receptor agonist, respectively, potentially serving as practical alternatives to oxytocin for treating hair-loss diseases.

This review discusses current challenges in selective androgen receptor modulator discovery and preclinical evaluation and reports no new results, emphasizing the need for basic research to improve safety and selectivity.

This study suggests that compounds from turmeric and bitter have potential antiviral activity against the influenza A virus by inhibiting the polymerase PA-PB1, warranting further experimental verification.

This study reported that paracrine factors, such as IGF-I and SCF, were reduced in balding hair follicles compared to non-balding ones, while inhibitory factors like TGFß-1 were increased, providing insights into the androgen action in hair follicles.

In this review, various expression systems for synthesizing recombinant collagen are compared, highlighting their efficiency, modification capabilities, and cost. Key purification techniques are also analyzed, and challenges like reducing R&D costs and improving safety protocols are identified.

This study found that using a combination of iontophoresis and liposomal delivery facilitated the effective intradermal administration of superoxide dismutase in rats, reducing oxidative skin damage from UV exposure.

This study found that keratin hydrogels extracted from human hair showed potential as biodegradable and biocompatible filler materials, promoting angiogenesis and cell proliferation in rat models.

This study found that methanolic extract of Eclipta alba leaves exhibited strong antibacterial effects against certain pathogens including methicillin-resistant Staphylococcus aureus, but it showed no activity against Mycobacterium tuberculosis, including drug-resistant strains.

This study found that partial protein extraction from keratinized tissues, such as hair and nails, reveals protein patterns distinct from whole protein extracts, including the presence of ubiquitin.

This review discusses the roles of extracellular vesicles in skin health and disease and reports no clinical results; the authors highlight potential therapeutic uses and call for more research.

This review highlights significant research trends and challenges in utilizing plant-derived extracellular vesicles for drug delivery and biomedical applications, emphasizing the need for standardized protocols and advanced purification technologies.

This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.

This study purified a transglutaminase enzyme from human epidermis that requires calcium or strontium for activity and forms cross-linked polymers, but its detailed activation mechanism remains unclear.

This study successfully used ATR FT-IR spectroscopy to uniquely identify or differentiate human hairs by detecting specific spectral features associated with individual hair characteristics and cosmetic residues on hair surfaces.

This study extracted water-soluble keratin particles from chicken feathers and verified their structural properties, observing no irritative potential on hen's eggs and positive physiological effects on human skin cells, suggesting their suitability for use on damaged or irritated skin.

In this study, researchers extracted soluble keratin proteins from chicken feathers and found they maintain structural integrity with potential uses for damaged skin, exhibiting no irritative effects in ex vivo settings on hen's eggs.

This review outlines the current state and future prospects of using layer-by-layer self-assembly for cell encapsulation in biomedical applications, such as cell-based biosensors, transplantation, and tissue engineering, while also discussing its limitations and potential advancements.

This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.

This study found that while extracellular matrix components like hyaluronic acid promoted larger organoid formation, other matrix components hindered hair follicle germ assembly in an in vitro model.

This study found that certain gene sets, including those involved in ligand-gated ion channel signaling and cell adhesion, are associated with Tourette syndrome, suggesting a potential neurobiological basis for the disorder.

Fibroblasts help understand androgen resistance at the cellular level.

This special issue reviews current challenges and innovative solutions for enhancing the penetration of topical formulations for human skin, reporting no new results.

This article discusses the potential for rejuvenating self-repair mechanisms to enhance regenerative medicine, but reports no new empirical findings.

This paper critically reviews recent advances in the use of keratin-based biomaterials, highlighting their potential applications in wound healing, drug delivery, and tissue regeneration due to their biocompatibility, biodegradability, and ability to support cell growth.

Hair increases in size when it absorbs water, and treatments like bleaching affect how much water it can take in.

In this study, researchers used computational modeling and virtual screening to identify two FDA-approved drugs, Tadalafil and Finasteride, that may effectively inhibit key proteins involved in melanoma progression, suggesting potential for new therapeutic strategies against aggressive melanoma.