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Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

Both mouse and rat models are effective for testing alopecia areata treatments.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Researchers found two new genetic variants linked to Alzheimer's disease.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Hairless mammals have genetic changes in both their protein-coding and regulatory sequences related to hair.

Some people have a genetic variation that makes them less effective at breaking down drugs.

The mouse models are effective for testing new hair loss treatments.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Innovative methods are reducing animal testing and improving biomedical research.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

A mother's diet at conception can cause lasting genetic changes in her child.

Advanced human skin models improve drug development and could replace animal testing.

Scalp hair follicle culture has limits for testing minoxidil's hair growth effects.

Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.

Hutchinson-Gilford Progeria Syndrome is a rare genetic disorder caused by a specific gene mutation, characterized by aging symptoms and managed by monitoring heart health and using low-dose aspirin.

The conclusion is that many small genetic variations influence claw disorders in cows, and using genomic selection could help reduce these disorders.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Intermediate hair follicles are a better model for studying hair growth and testing hair loss treatments.

The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.

Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.

Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.