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Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Smoking may contribute to hair loss in men.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Hair follicle regeneration needs special conditions and young cells.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Muscles and nerves that cause goosebumps also help control hair growth.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Scientists found a gene in mice that causes early hearing loss.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Celiac disease can cause skin problems that may get better with a gluten-free diet.