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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

Hormones and stretching both needed for nipple area skin growth in mice.

Hox genes control hair follicle stem cell regeneration in different body regions.

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

Nanoformulations improve luteolin's effectiveness as a cancer treatment.

Dupilumab for skin problems might reactivate hair loss in some patients.

Belimumab effectively controls SLE disease activity and reduces steroid use.

The document concludes that hair restoration has advanced significantly, with FUE becoming more popular, and stresses the importance of physician training and ethical practices in the field.

Dr. Russell Knudsen's system classifies hair grafts by class, shape, and size for clearer communication in hair restoration surgery.

Finasteride reduces urinary issues and surgery need in men with enlarged prostates by over 50%.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Finasteride for hair loss may cause depression, affecting sleep and relationships.

Understanding how fetal wounds heal could help improve healing in adults.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.

Older rats more affected by minoxidil's cardiotoxic effects than younger rats.

No link found between aromatase gene and female hair loss.

Acitretin can cause excess tissue growth and hair loss.

A new hair loss classification for women improves treatment, but careful patient selection is crucial for successful hair transplantation.

The conclusion is that surgeons should carefully create a natural-looking occipital hairline in hair transplants to avoid detection.

Syntax-based neural networks can match Transformers in handling unseen sentences.

Sodium hypochlorite can effectively prevent and remove Staphylococcus aureus biofilms in atopic dermatitis at high enough concentrations.

Pre-trained Transformers need extreme retraining to perform well on DarkNet data.

The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.