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JAK inhibitors effectively improve hair regrowth in alopecia areata with an acceptable safety profile.

Quick, selective detection of tadalafil and finasteride in human plasma developed.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Father's finasteride use may affect son's fertility and testicular function.

Immune cells are essential for early hair and skin development and healing.

Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Dandruff is mainly caused by a scalp reaction to yeast, can worsen hair loss, and antifungal treatments may help.

Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.

Researchers identified new compounds in Platycladi Cacumen and found variations in its flavonoid content, which could aid in its quality control.

Researchers created hair-inducing human cell clusters using a 3D culture method.