54 citations,
January 2023 in “Signal Transduction and Targeted Therapy” New therapies are being developed that target integrin pathways to treat various diseases.
14 citations,
May 2022 in “Asian Journal of Pharmaceutical Sciences” New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
56 citations,
March 2016 in “International Wound Journal” Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
January 2025 in “Burns & Trauma” Skin organoids help improve wound healing and tissue repair.
February 2024 in “PloS one” Tofacitinib and adalimumab are promising treatments for cicatricial alopecia with few side effects.
110 citations,
April 2020 in “Advances in Wound Care” Nanotechnology shows promise for better chronic wound healing but needs more research.
20 citations,
March 2005 in “Current Medicinal Chemistry” New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.
17 citations,
April 2017 in “International Journal of Biological Macromolecules” Monoolein-alginate beads help heal wounds by controlling moisture and effectively delivering adenosine to the skin.
30 citations,
May 2014 in “American Journal of Clinical Dermatology” The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.
35 citations,
December 2020 in “International Journal of Molecular Sciences” Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.
13 citations,
November 2021 in “Biomedicines” Plasma-activated liquid can kill harmful cells, speed up wound healing, and potentially treat cancer without damaging healthy cells.
April 2024 in “Journal of translational medicine” Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
1 citations,
August 2024 in “Polymers” Bacterial cellulose is a promising material for biomedical uses but needs improvements in antimicrobial properties and degradation rate.
64 citations,
July 2011 in “Dermatologic Therapy” Scalp cooling can prevent chemotherapy-induced hair loss, and certain treatments can speed up hair regrowth, but more research is needed for better treatments.
119 citations,
March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
8 citations,
May 2023 in “Gels” Chitosan hydrogels are promising for repairing blood vessels but need improvements in strength and compatibility.
January 2025 in “Pharmaceuticals” Peptide-based hydrogels are promising for healing chronic wounds effectively.
3 citations,
January 2010 in “Elsevier eBooks” The document describes various skin conditions, their features, and treatments but lacks detailed study size information.
8 citations,
December 2020 in “The FASEB Journal” Blocking adenosine A2B receptor may prevent or treat hearing loss.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
14 citations,
October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
35 citations,
November 2020 in “Dermatologic Therapy” Severe COVID-19 may cause hair loss, and doctors recommend supplements and topical treatments to manage it.
14 citations,
July 1987 in “Dermatologic Clinics” The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.
March 2012 in “Hair transplant forum international” Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.
21 citations,
February 2009 in “Journal of the American Academy of Dermatology” Some cases of tinea capitis, a fungal scalp infection, can look like scarring hair loss due to the body's immune response and the fungus itself.
95 citations,
May 2012 in “British Journal of Dermatology” Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
January 2020 in “International Journal of PharmTech Research” A man with severe leprosy developed painless ulcers and numbness, treated successfully with multiple drugs and vitamins.
23 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
10 citations,
August 2021 in “Frontiers in cell and developmental biology” Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
2 citations,
September 2017 in “Biotechniques/BioTechniques” Researchers created a mouse cell line to study hair growth and test hair growth drugs.