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This article proposes a novel approach to remodel the microenvironment of radiotherapy-induced skin defects, highlighting the lack of a standardized animal model as a barrier to progress in this field.

This review highlights the rising interest in exosomes within regenerative medicine, emphasizing their role as communicators that offer standardized manufacturing and ease of use over stem cells. Yet, exosomes complement rather than replace stem cells, each holding unique positions within biological processes.

This study found that dermal papilla cells in human hair follicles exhibit stronger expression of VEGF mRNA and protein compared to other follicular cells, suggesting their key role in angiogenic processes related to hair growth.

This study found that nanoparticles can penetrate the skin, but artifacts produced during specimen preparation complicate accurate observation, and proposed a method for reducing errors in imaging quantum dots as tracers.

This study found that lymphatic vessels promote hair follicle growth in mice and may represent new therapeutic targets for hair loss conditions.

This study conducted a review of clinical studies from 2020 to 2025 on exosome-based dermatologic therapies, reporting improvements in skin conditions like wrinkles and scars, though with noted limitations such as small sample sizes and potential conflicts of interest.

This review discusses the chemical stability of protein envelopes found in the epidermis and other stratified squamous epithelia, but reports no new clinical results.

Exosomes from stem cells might help treat hair loss.

This study found that human TMEM2 does not function as a hyaluronidase but is involved in regulating hyaluronan metabolism.

This study found that using copper-doped mesoporous silica nanoparticles to deliver IL-1Ra and copper ions effectively reduced arterial stenosis, plaque burden, and macrophage infiltration in atherosclerosis, by promoting macrophage apoptosis and providing anti-inflammatory effects.

This study found that miRNA biogenesis, facilitated by Dicer and Drosha, is crucial for adult hair follicles' growth and regeneration, highlighting their multiple roles during the hair follicle growth cycle.

In this mouse study, researchers found that nanoparticles loaded with umbilical cord-derived stem cell membranes and minoxidil enhanced hair growth by improving drug solubility and transdermal delivery, increasing VEGF, IGF-1, MKI67, and CTNNB protein levels in skin tissue compared to regular minoxidil.

This study found that intracorneal vacuoles were common in various parakeratotic skin diseases in dogs, but large vacuoles were exclusively observed in congenital follicular parakeratosis.

This study found that the interdigital gland of Vembur sheep has larger secretory lobules in males than females, producing various compounds for chemical communication and foot protection.

This review found that mesenchymal stem cells and their derived exosomes are a potentially safe and well-tolerated treatment for lung healing in patients with COVID-19.

This review discusses the design, properties, and potential applications of smart microneedles, with no new clinical results presented.

In this study, researchers found that tubular VCAM1 expression in transgenic mice and human kidney transplant biopsies precedes nephron loss and fibrosis, indicating its potential as an early biomarker for tubular fate and adverse kidney outcomes.

This article reviews potential pathomechanisms of vitiligo, emphasizing membrane alterations involving cholesterol and cardiolipin, but reports no new clinical findings.

This study found that the combination of recombinant growth factors and plant-derived extracellular vesicles significantly improved scalp regulation, hair growth, thickness, and density, and reduced hair shedding in the tested formulation by Day 56.

This study found that exosomes derived from hair follicle neural crest stem cells significantly promoted nerve regeneration in injured neurons, particularly when overexpressing miR-214-3p, which enhanced axon extension and motor function recovery in both in vitro and in vivo models.

This review discusses the application of mesotherapy in dermatology and trichology, noting its potential benefits and issues, but reports no new clinical results.

In this animal study, topical VEGF gel increased hair growth and thickness in Mesocricetus auratus, although it was not completely inert, highlighting the need for further toxicity confirmation.

This study found that a lentiviral array of reporters can identify lineage-specific promoters and pathways in mesenchymal stem cell differentiation, aiding in the prediction of signaling pathway effects.

This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.

This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.

This study reviews lipid-based nanocosmeceuticals and reports that they enhance therapeutic effectiveness in dermatological applications by improving skin hydration, reducing wrinkles, and effectively managing conditions like psoriasis and eczema, though further large-scale trials and regulatory alignment are needed for clinical use.

This review discusses technological advances in liposome systems for drug delivery and reports no new clinical results; it highlights the clinical acceptance and market presence of liposomal products.

This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.

This article highlights exosome-based targeted drug delivery using DARPin G3 proteins as a promising approach for treating aggressive HER2-positive breast cancer but reports no new clinical results.

This study found that the newly developed microarray patches for intradermal delivery of finasteride showed high drug content and significantly improved skin deposition compared to existing methods.