Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review synthesizes existing research on the multilayered defense system of the skin, highlighting how physical, chemical, immune, and microbial barriers work together to maintain skin health, with disruptions in one often leading to broader barrier dysfunctions.

This study demonstrated that while the proposed placebo microneedle stamp design was partially successful in blinding participants with low skin sensitivity, further development of suitable placebo controls is needed.

USB videodermatoscopes are a practical and affordable alternative for diagnosing skin conditions.

In this study, Sox13 was identified as a novel marker for early hair follicle development and differentiation in mice, though it appears to be dispensable for overall epidermal and adnexal development.

In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.

In this study, researchers observed that mechanosensory neurons initially develop similar morphologies across different skin regions but diverge post-natally, adapting to the type of skin they innervate, with bone morphogenetic protein signaling crucial for forming Meissner corpuscles in glabrous skin.

This review highlights that two-photon excitation microscopy is a valuable tool for visualizing live skin structures and immune responses at high resolution, though its clinical use is hindered by safety and cost issues.

This study describes new devices, "HairMeasure" and "Scalp Zone Identifier," which offer an economical method to calculate Hair Mass Index without disposable materials.

In this study, researchers observed a high degree of plasticity in somatosensory axons innervating Merkel cells in adult mouse skin, with both epithelial and neural components exhibiting dynamic remodeling, highlighting intricate epithelial-neural interactions in maintaining homeostasis.

This study introduced mechanical setups to analyze the mechanical properties of root hairs in Arabidopsis thaliana, finding that axial stiffness primarily relates to tip compression and turgor pressure, confirmed by independent methods adapted from work on animal cells.

The abstract did not include specific study details, results, or conclusions; therefore, it remains unclear what this research aimed to investigate or reported.

This study suggests that MultiDomain Peptide hydrogels may support wound healing in diabetic mice by accelerating closure and promoting tissue regeneration, though they did not inhibit bacterial growth in infected wounds as expected.

This study found that multiparametric ultrasound effectively detects real-time scalp changes caused by vasoconstrictive cosmetic agents, demonstrating its potential as a non-invasive tool for evaluating trichological treatments.

This study explored the use of multiphoton microscopy to monitor changes in tumors and surrounding tissues in breast cancer patients undergoing neoadjuvant chemotherapy, finding it may effectively detect treatment response at cellular levels without using exogenous contrast agents.

This study developed a digital tool for quantitatively assessing hair in androgenetic alopecia, achieving an average accuracy of 79.45% for counting hairs and 68.19% for measuring hair size compared to human evaluation.

This study developed a hat-shaped device with wearable sensors to estimate scalp moisture content using machine learning, demonstrating that it can provide accurate measurements comparable to professional scalp analyzers without the need for high-cost equipment.

This study revisits and reproduces Felix Pinkus' concept of the vitreous membrane in hair follicles, suggesting these structures may play a role in differentiation or nutrition due to their location in metabolically dynamic regions.

This commentary reviews the evidence for microinflammation's role in pattern hair loss and suggests that further studies with age- and sex-matched controls are needed to substantiate the findings.

This study reports that microencapsulation of therapeutic cells with contrast agents enables visualization across multiple imaging modalities, potentially improving cellular immunoprotection and tracking after transplantation.

This study developed a high-resolution phototrichogram system that can automatically and accurately assess hair growth metrics in cosmetic trials, achieving over 90% correlation with manual measurements.

This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.

This review discusses the potential of microneedle arrays for drug delivery and in the cosmetic market, but reports no new clinical results; factors for commercial therapeutic use are explored.

This study found that follicular acantholysis is a common histopathological feature in pemphigus, with differences in depth between pemphigus vulgaris and pemphigus foliaceus lesions that may aid in diagnosis.

This review discusses micro-segmental hair analysis for forensic toxicology, emphasizing its potential to provide detailed drug distribution profiles and its application in investigations, while noting the method's limitations and future perspectives.

In this study, a chronotherapeutic bilayer dressing system showed enhanced diabetic wound healing in a model by reducing inflammation through polyphenols and promoting repair with sustained PDGF-BB delivery, leading to faster re-epithelialization and hair follicle regeneration.

This article discusses scalp micropigmentation as a noninvasive method to conceal various forms of hair loss and scalp abnormalities and reports no clinical results; the authors highlight its safe and effective application.

This study designed a micromold template for creating controlled-sized, multicellular tumor spheroids, finding that HEK-293 cells formed consistent spheroids with high circularity and viability after 7 days, influenced by cell seeding density and treatment conditions.