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In this study, researchers reported that IL-17C plays a key pro-inflammatory role in human skin diseases and may be a promising therapeutic target for inflammatory skin conditions.

This study found that DC-HIL+ myeloid derived suppressor cells are increased in the blood and skin of patients with cutaneous lupus erythematosus and show immunosuppressive properties.

This study found that Avicennia marina extract and its active compound avicequinone C inhibit enzymes and receptors related to androgenic alopecia, potentially supporting hair growth in cultured dermal papilla cells.

Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.

This study found that finasteride treatment reduced urinary androgen and prostaglandin levels in male pattern baldness patients to levels similar to healthy controls.

This study found that 1550-nm Er:Glass fractional laser treatment significantly increased hair density and shaft diameter in patients with androgenetic alopecia, though the mechanism may not involve Wnt10A or IGF-1 expression.

This review discusses the current and emerging methods for profiling skin microbes to advance our understanding of the microbiome in skin disease, but it reports no new clinical findings.

This review discusses the role of hair follicle bacterial colonization in immune responses and the pathogenesis of alopecia but reports no new clinical results.

This study suggests that Lindera strychnifolia root extract may help restore a healthy microbial balance on the scalp in men with androgenetic alopecia after 83 days of treatment.

This study found that patients with androgenetic alopecia showed distinct scalp bacterial imbalances compared to healthy individuals, which were associated with unhealthy lifestyles. These microbial changes might contribute to follicular inflammation, potentially accelerating hair loss in these patients.

This narrative review discusses various microbes associated with fermentation and diseases in plants, animals, and humans, reporting no new research results.

This study analyzed pexidartinib-associated adverse events from FDA data and reported common events such as hepatic issues and systemic reactions. It highlighted sex-specific susceptibilities and reinforced the need for risk mitigation and long-term monitoring in tenosynovial giant cell tumor management.

This review provides a comprehensive guide to the human microbiome and reports no new experimental results; it highlights the impact of modern lifestyles on microbial homeostasis and the necessity of conservation efforts.

The researchers reported that hair follicle development and commensal microbe colonization promote the accumulation of regulatory T cells in neonatal skin, with the Ccl20-Ccr6 pathway playing a key role in this process.

This study found that mouse skin CD4(+) memory T cells are in equilibrium with the circulation under steady state but increase in specific clusters in response to infection or inflammation.

This study found that trilostane was effective in resolving symptoms such as polyuria and polydipsia in many dogs with pituitary-dependent hyperadrenocorticism, with significant hormone level reductions observed.

This study reported that continuous intravenous dextran sulfate was toxic and ineffective as a treatment for symptomatic HIV infection, as it did not improve surrogate markers and caused significant side effects.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

In this study, human dermal fibroblasts were identified as natural host cells that support productive Merkel cell polyomavirus infection, and the MEK antagonist trametinib was introduced as an effective inhibitor to control the virus.

This review discusses the clinical manifestations and immune response to Rhodococcus equi infection in foals but reports no new clinical results.

In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.

This study found that in healthy men, higher levels of free testosterone were associated with a stronger immune response to the influenza vaccine, suggesting androgens may function as immunomodulators rather than strict immunosuppressants.

This study found that simultaneously inhibiting both KLK5 and KLK7 proteases completely rescued skin barrier defects in a mouse model of Netherton syndrome, suggesting both should be therapeutic targets.

This study suggests that Notch1 acts as a key signal in skin epithelium, promoting immune cell recruitment and aiding in normal skin repair after damage.

This review discusses the features of regulatory T cells and the modulation of Foxp3, emphasizing post-translational modifications' impact on Treg function but reports no new clinical results.

This study found that antibiotic-induced gut dysbiosis, particularly overgrowth of Lactobacillus murinus, can lead to hair loss in mice by depleting biotin.

This study found that beta-caryophyllene enhanced re-epithelialization in cutaneous wounds of female mice, suggesting its potential for improving wound healing through multiple pathways.

This study identified distinct human and bacterial protein profiles in sebaceous follicular casts, with acne samples showing proteins linked to inflammation and normal samples showing proteins involved in stress protection.

This research reported that squarticles, nanoparticles made from sebum-derived lipids, enhanced the follicular delivery and skin accumulation of diphencyprone and minoxidil, indicating effective drug deposition with reduced systemic absorption in alopecia treatment.