DC-HIL+ Myeloid-Derived Suppressor Cells Are Elevated in the Peripheral Blood and Lesional Skin of Cutaneous Lupus Patients

The document summarized findings from several studies on skin conditions. It reported that patients with palmoplantar pustulosis, especially those with pustulotic arthro-osteosis, have oral dysbiosis. High amphiregulin expression in skin was linked to increased risk and mortality in acute graft-versus-host disease. BLZ-100 (tozuleristide) was found to be safe and potentially effective for imaging malignant skin cancer tissue. In androgenetic alopecia, 1550-nm erbium-glass fractional laser treatment was shown to increase hair density and shaft diameter without affecting Wnt10A or IGF-1 mRNA levels. Additionally, DC-HIL+ myeloid-derived suppressor cells were found to be elevated in the blood and skin of cutaneous lupus erythematosus patients, indicating a potential immunosuppressive role. The document also mentioned the significance of IL-17C in inflammatory skin diseases as a therapeutic target.