October 2021 in “Journal of Investigative Dermatology” This study found that fibroblasts from mature skin showed significantly reduced mechanical force production compared to young skin fibroblasts, suggesting age-related changes in cellular mechanical properties.
September 2022 in “Journal of Plastic and Reconstructive Surgery” This article discusses the public interest in mesotherapy for rejuvenation, noting inconsistent evidence of its efficacy, and suggests that revised standards for injection depth may improve patient outcomes.
January 2018 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Scalp micropigmentation is a process where tiny dots of pigment are tattooed onto the scalp to create the appearance of a shaved head or fuller hair.
January 2023 in “Skin appendage disorders” This review discusses the scalp microinfusion MMP® technique for hair loss treatment and reports no new results; it emphasizes the need for more standardized studies.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that ECMs produced by papillary fibroblasts showed the largest fibers and supported keratinocyte differentiation better than reticular fibroblast matrices, informing biomimetic material design for skin tissue engineering.
30 citations
,
September 2009 in “Seminars in Cutaneous Medicine and Surgery” This review outlines how dermoscopy enhances diagnostic accuracy by up to 30% compared to unaided visual inspection and explores its potential as a research tool without presenting new research findings.
Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
44 citations
,
July 2015 in “JAMA Facial Plastic Surgery” This review details the advancements and benefits of fractional erbium:YAG resurfacing lasers for treating photoaging, acne scarring, and dyschromia, but it presents no new clinical results.
1 citations
,
November 2016 in “Experimental and Therapeutic Medicine” In this study using guinea pigs, the low-dose 800 nm semiconductor laser was found to effectively treat skin blackheads and coarse pores by promoting hair follicle cell apoptosis, while maintaining PCNA expression levels in sebaceous glands.
82 citations
,
March 2012 in “Development” This study found that deleting the miRNA processing enzymes Drosha and Dicer from mouse skin epithelial cells disrupted normal hair follicle development and maintenance, leading to follicular degradation and stem cell loss during the growth phase.
February 2026 in “Journal of drug targeting” This study found that combining laser ablation with nanoparticulate drug formulations effectively enhanced the skin and follicular delivery of hydrophilic drugs like minoxidil and minocycline in preclinical models.
January 1997 in “Fundamental & Clinical Pharmacology”
11 citations
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December 2006 in “Expert Review of Dermatology” This article examines the emerging role of dermoscopy in skin cancer diagnosis and reports no new clinical findings; the authors highlight its potential to enhance dermatological practice.
4 citations
,
January 2022 in “Current pharmaceutical design” This review discusses the benefits and applications of microsponges delivery systems in drug delivery, particularly for topical treatments, and reports no new clinical findings.
8 citations
,
March 2025 in “Journal of Drug Delivery Science and Technology” Dissolvable microneedles are a promising, painless method for effective skin treatments.
50 citations
,
December 2017 in “Nanoscale” This study found that polymeric micelle formulations significantly improved the targeted delivery of adapalene to hair follicles compared to standard Differin® products, which suggests potential advantages in treating hair follicle-related conditions and reducing side effects.
This chapter reviews the combined use of platelet-rich plasma and microneedling for cosmetic enhancement but reports no clinical results; the authors highlight existing uses and suggest potential synergistic benefits in dermatology.
January 2026 in “Forum Dermatologicum” This review concluded that LED-based photobiomodulation is generally safe and effective for certain dermatologic conditions, though consumer devices often show less efficacy compared to professional systems.
38 citations
,
June 2016 in “Journal of Tissue Engineering and Regenerative Medicine” This study demonstrated that implanting μm-scale full-thickness columns of human skin tissue into immunodeficient mice restored key features of normal human skin, suggesting potential for human wound repair with minimal donor site morbidity.
This pilot study employed in-vivo multiphoton microscopy to visualize pigment-producing melanocytes in vitiligo patients, aiming to enhance understanding of treatment impacts and potentially improve transplantation therapies.
55 citations
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March 2018 in “Journal of pharmacy & pharmaceutical sciences” This article reviews the applications of microneedle technology in drug delivery, dermatology, and cosmetics, but it presents no new experimental or clinical findings.
This study suggests that PDRN may enhance wound healing by reducing MIR135b expression, which in turn increases FOXO1 expression in keratinocytes.
November 2025 in “Bioengineering” In this study, researchers used a 3D printing technique to spatially pattern human dermal papilla cell spheroids in a collagen matrix, enhancing skin and hair regeneration in a mouse model, with notable upregulation of key genes for hair follicle formation compared to traditional cell cultures.
19 citations
,
April 2019 in “Journal of the European Academy of Dermatology and Venereology” This study found that acne lesion formation involves early hyperkeratinization and inflammation around hair follicles, creating a self-sustaining cycle that may progressively worsen acne.
2 citations
,
April 2020 in “PubMed” December 2018 in “Dermatologic Surgery” This article outlines the comprehensive content of the Dermatologic Surgery journal, which covers a wide range of topics related to cosmetic and reconstructive skin surgery, including skin cancer, but presents no new clinical results.
September 2017 in “Journal of Investigative Dermatology” RCS-01 is safe and may help rejuvenate aging skin.
2 citations
,
November 2018 in “Modern Applied Science” This study proposed a method to automatically detect and replace hair in dermoscopy images, demonstrating high sensitivity and specificity in melanoma diagnostics.
January 2023 in “Indian Dermatology Online Journal” This article reviews the indications for micropigmentation in dermatological conditions like stable vitiligo and alopecia, but presents no new clinical results.
64 citations
,
December 1982 in “Archives of Dermatology” This article reviews various office treatments for common cosmetic issues but does not report any new clinical findings, focusing instead on discussing techniques like dermabrasion and chemical peels.