9 citations
,
October 2022 in “Journal of Molecular Neuroscience” This study reports a novel LSS gene mutation in an Egyptian family with alopecia intellectual disability syndrome 4, expanding the known clinical and genetic features of the condition.
35 citations
,
September 2009 in “Psychoneuroendocrinology” Early-life neurosteroid changes affect adolescent exploration and adult behavior.
34 citations
,
December 1995 in “Pediatric Dermatology” In this study, researchers reported a 0.11% occurrence of congenital triangular alopecia, recommending surgical treatment for women but not for men due to later potential development of androgenic alopecia.
17 citations
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May 1995 in “Anatomy and Embryology” This study found that treating neonatal mice with the neurotoxin 6-OHDA resulted in temporary hair loss and thinner skin compared to control mice, linking sympathetic neurons to hair growth and skin thickness.
February 2021 in “Journal of the Korean Ophthalmological Society” This study examined a 7-year-old girl with trichomegaly of the eyelashes, showing no significant underlying or observable cause, suggesting a spontaneous occurrence.
10 citations
,
April 2020 in “PloS one” This study found that mitochondrial dysfunction due to Crif1 deficiency in hair follicle stem cells significantly slows the hair growth cycle in adult mice but does not impact the maintenance of HFSC populations.
This case report describes a pediatric patient with diabetes mellitus type 1 who uniquely also developed membranous glomerulonephritis and alopecia areata, highlighting a rare association of these autoimmune conditions.
20 citations
,
July 2013 in “European Journal of Oral Sciences” This study found a novel PAX9 gene mutation that may cause tooth agenesis and trichodysplasia in a studied family.
April 2023 in “Journal of Investigative Dermatology” This study suggests that MPZL3, a mitochondrially localized protein, may play an integral role in regulating hair follicle cycles, with potential therapeutic implications for hair growth disorders if findings translate to humans.
August 2018 in “Journal of Investigative Dermatology” This study found that centrosomes, unlike cilia, are essential for proper epidermal and hair follicle development in mice, with these effects being dependent on the presence of p53.
In this case study, researchers reported the first documented instance of malignant transformation of congenital triangular alopecia into basal cell carcinoma in a 48-year-old woman, underscoring the importance of assessing long-standing alopecic areas for malignancy.
2 citations
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July 2018 in “Journal of Cosmetic Dermatology” This commentary discusses how common latent viruses might contribute to male-pattern baldness through mechanisms involving transcription factor deficiency and overexpression of specific proteins, based on a concept called microcompetition; it reports no new research results.
1 citations
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July 2019 in “Case reports in dermatology” This case report describes the first known instance of loose anagen hair syndrome in a Southeast Asian child, a 13-year-old Thai boy with hair thinning and excessive shedding on the frontal scalp.
January 2011 in “Revista Portuguesa de Endocrinologia Diabetes e Metabolismo” This article presents a case of congenital adrenal hyperplasia and myelolipoma in a 56-year-old woman, describing her symptoms and characteristics without offering new clinical results.
October 2024 in “Dermatology Practical & Conceptual” In this study, the authors evaluated 200 Egyptian children with focal non-cicatricial alopecia, finding that alopecia areata (42%) and tinea capitis (40.5%) were the most prevalent causes. Trichoscopy identified unique features for each condition, enhancing diagnosis and management.
This case study indicates that older patients with NMOSD may show favorable clinical improvements with aggressive treatment, even when the intervention is initiated later in the disease course.
November 2023 in “Scientific Repository of Open Access of Portugal (RCAAP)” This study reports on a severe case of alopecia areata in a healthy eight-year-old boy, highlighting persistent hair loss over four years of treatment before full regrowth, and noting that alopecia areata might indicate the early onset of autoimmune disease symptoms.
1 citations
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January 2017 in “대한피부과학회지” This study observed that male pattern hair loss patients are getting diagnosed earlier and presenting with milder forms, possibly due to early puberty, and noted frequent familial predisposition and comorbidities like seborrheic dermatitis.
3 citations
,
April 2016 in “International Journal of Dermatology” This article presents a clinicopathologic challenge involving early leonine facies with alopecia in a young man and reports no new clinical results.
2 citations
,
June 2016 in “International Journal of Medical Research and Review” This study found that Epstein pearls and Mongolian spots are the most common skin lesions in newborns in India, influenced by interracial, environmental, and hormonal factors.
April 2019 in “Dermatology reports” This case study reported that scalp dermoscopy, or trichoscopy, provided a useful noninvasive method to evaluate and confirm hair regrowth in a child treated for tinea capitis.
65 citations
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January 2005 in “American journal of clinical dermatology” This article reviews the diagnosis and treatment of tinea capitis in children, noting that newer antifungal agents can offer effective systemic therapy alongside supportive topical treatments; it reports no new clinical findings.
3 citations
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January 2002 in “Pediatric Drugs” This review discusses treatments for tinea capitis, noting that while griseofulvin remains a common choice, shorter treatment options like terbinafine, itraconazole, and fluconazole show promise but require further studies.
March 2003 in “中華皮膚科醫學雜誌” This report describes a patient with trichothiodystrophy exhibiting both specific hair abnormalities and developmental delay, contributing to the understanding of this rare disorder's clinical presentation.
33 citations
,
July 2007 in “Journal of cell science” This study found that knocking out the transactivation domain of Miz1 in mouse keratinocytes disrupted hair follicle orientation, caused irregular pigmentation, and increased keratinocyte proliferation, indicating Miz1's role in hair follicle development and morphogenesis.
1 citations
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November 2023 in “Cureus” This study highlights a case of a 12-day-old female with Bloch-Sulzberger Syndrome, underscoring the need for early diagnosis based on skin symptoms to manage potential complications in other organs effectively.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the mutant hairless rhino bald protein in mice interacts with the vitamin D receptor but cannot repress its transactivation and shows abnormal cellular localization.
January 2022 in “Clinical Cases in Dermatology” This case report describes successful treatment of a 7-year-old girl with gray patch tinea capitis using oral micronized griseofulvin and topical ketoconazole shampoo, resulting in complete clinical and microscopic clearance.
4 citations
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July 2013 in “The Journal of Dermatology” This article reports a case of lupus miliaris disseminatus faciei affecting the scalp, which led to scarring hair loss, but it provides no new experimental findings.
9 citations
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April 1985 in “Archives of Dermatology” This case report describes a 7-year-old boy with Netherton's syndrome, highlighting the identification of the tricorrhexis invaginata hair defect using a photographically illustrated scalp biopsy, which had not been visually documented before.