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The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.

Metformin helps manage weight, blood pressure, and hormonal imbalances in PCOS patients.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

New treatments for PCOS show promise, including both medication and non-medication options.

Eating less can improve stem cell function and increase lifespan.

Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.

Metabolism plays a key role in determining stem cell fate.

Targeting lipid metabolism can help treat advanced, resistant cancers.

Altering SSAT affects fat metabolism and body fat in mice.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

A low-starch/low-dairy diet may help overweight women with PCOS lose weight and improve metabolism, but more research is needed.

Antioxidant therapy, especially with selenium, can improve skin aging in patients with Metabolic Syndrome.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Androgenetic alopecia is linked to aging due to inflammation, oxidative stress, and hormonal changes.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Retinoic acid affects male and female muscle energy use and function differently.

Optical imaging and light therapy show promise for diagnosing and treating liver injury caused by surgery.

Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.

Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Small molecule IM boosts hair growth by changing stem cell metabolism.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Metabolic syndrome reduces effectiveness of hair loss treatment.