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Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.

Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.

Poor blood supply in hair follicles is linked to nutrient deficiency in patients with female pattern hair loss, and adding more nutrients could potentially fix this.

Vitamin D deficiency is linked to a higher chance of metabolic syndrome in women with PCOS.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Biotin treatment improves symptoms of biotinidase deficiency, but some neurological damage may be permanent.

Early diagnosis and biotin treatment are crucial for infants with biotinidase deficiency to prevent severe complications.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Biotin supplements can effectively treat hair loss and skin issues in certain enzyme deficiencies.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Early diagnosis and treatment of biotinidase deficiency are crucial to prevent vision problems.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Higher vitamin D levels are linked to higher iron levels in Korean women without metabolic syndrome, but not in those with it.

Combined oral contraceptives improve skin, hormone levels, and quality of life in women with PCOS.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.

A baby with a rare metabolic disorder developed a rash not cured by zinc alone, likely due to both zinc and amino acid deficiencies.

Hypothyroidism may worsen metabolic problems like insulin resistance and obesity in women with PCOS.