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Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

The document explains the genetic causes and characteristics of inherited hair disorders.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.

Calcium is important for stem cell function and maintenance, especially in blood and skin cells.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Itraconazole may cause low platelet and white blood cell counts.

Older patients with Cushing's syndrome often have different symptoms and treatment outcomes compared to younger patients.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Not getting enough vitamin D can lead to health problems, so kids over one should get 600 IU/day.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Zinc is important for skin health, and supplements can help treat various skin and hair disorders, but more research is needed for conditions like psoriasis and vitiligo.