4 citations
,
June 2025 in “Cochrane Database of Systematic Reviews” This Cochrane review found no clear superiority among treatments for central serous chorioretinopathy, with low-dose photodynamic therapy, supplements, and eplerenone showing slightly higher probabilities of improving visual acuity, but evidence remains uncertain due to biases and small study sizes.
4 citations
,
June 2025 in “Frontiers in Immunology” This study found an association between atopic dermatitis and autoimmune diseases in both adults and children, with women more likely to experience these complications, but further research is needed due to limited participant numbers.
4 citations
,
February 2025 in “Journal of Autoimmunity” This systematic review and meta-analysis reports a significant familial risk of autoimmune and related conditions among relatives of individuals with Alopecia Areata, highlighting the importance of comprehensive family monitoring and genetic counseling.
4 citations
,
March 2024 in “Food & Nutrition Research” This study found that a ketogenic diet was linked to lower weight loss outcomes in obese or overweight women with PCOS.
4 citations
,
December 2023 in “Frontiers in Pharmacology” This study found that topical metformin was as effective as triple combination cream in reducing melasma severity, with minimal adverse events.
4 citations
,
June 2023 in “Frontiers in immunology” This study found that JAK inhibitors effectively improve alopecia areata outcomes, as indicated by SALT scores, but they were associated with an increased risk of adverse effects, with 921 out of 1508 patients experiencing adverse reactions.
4 citations
,
April 2023 in “Autoimmunity reviews” This systematic review and meta-analysis reports that patients with alopecia areata have significantly higher serum levels of IL6 and CRP, and lower levels of vitamin D, compared to healthy controls.
4 citations
,
November 2022 in “Frontiers in Medicine” This study found that people with alopecia areata have a higher likelihood of experiencing anxiety and depression, and a moderate negative impact on their quality of life compared to healthy individuals.
4 citations
,
December 2021 in “Archivio italiano di urologia andrologia” This review found that patients taking antiandrogens, 5 alpha-reductase inhibitors, and spironolactone have an increased risk of developing gynecomastia, potentially due to hormonal changes.
4 citations
,
October 2018 in “International Braz J Urol” This study found no positive association between the use of 5α-reductase inhibitors and the risk of male breast cancer.
3 citations
,
August 2025 in “International Journal of Molecular Sciences” This study found that women with PCOS have significantly higher prevalence and levels of thyroid autoantibodies, with these elevated levels suggesting a potential independent autoimmune activation associated with PCOS.
3 citations
,
March 2025 in “Journal of Clinical Medicine” This study found that Ritlecitinib significantly reduced hair loss in patients with alopecia areata by lowering SALT scores at weeks 12 and 24 compared to placebo, with acceptable safety but increased minor side effects like headaches and acne.
3 citations
,
February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY” This systematic review and meta-analysis found 30 genetic loci associated with skin ageing phenotypes, noting shared biological pathways in aspects like pigmentation and wrinkling; researchers suggest further studies targeting the same SNP across populations could clarify these associations.
3 citations
,
December 2024 in “EClinicalMedicine” Anti-androgens are not better than birth control pills for PCOS, but can help with excess hair if pills don't work.
3 citations
,
August 2024 in “Middle East Fertility Society Journal” This study analyzed 19 articles and found that vitamin D significantly improved the hormonal profile in women with PCOS, with greater effects observed after 8-week interventions compared to 12-week ones.
3 citations
,
June 2023 in “European heart journal open” This study found that oligo-amenorrhea/menstrual irregularity in women is associated with an increased risk of overall cardiovascular disease, coronary heart disease, and myocardial infarction, while evidence linking hyperandrogenism or polycystic ovaries to cardiovascular disease remains mixed or unexplored.
3 citations
,
April 2022 in “Dermatologic Surgery” This systematic review found that photobiomodulation therapies using ultraviolet and infrared light effectively treated alopecia areata, while red and infrared light treatments were effective for androgenetic alopecia.
3 citations
,
January 2022 in “Journal of The American Academy of Dermatology” This study found that sunscreen and moisturizer use was associated with a higher likelihood of developing frontal fibrosing alopecia in the reviewed studies.
3 citations
,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study suggests that platelet-rich plasma may improve pain and function in patients with partial-thickness rotator cuff tears and tendinopathy short-term, but the long-term benefits are unclear.
2 citations
,
February 2025 in “Medicine” This study found that among individuals with hair loss-related conditions, there was a significant association between alopecia and anxiety disorders, with affected individuals experiencing anxiety more frequently.
2 citations
,
September 2024 in “Journal of Dermatological Treatment” In this study, combining compound glycyrrhizin with topical minoxidil was more effective and as safe as minoxidil alone for treating alopecia areata.
2 citations
,
February 2024 in “Medicine” In this study, researchers found that the rs3118470 mutation in the IL2RA gene significantly increases the risk of developing alopecia areata, and they emphasize the need for future research with larger, more diverse populations to validate these results.
2 citations
,
August 2023 in “Journal of Cutaneous Medicine and Surgery” This study concluded that platelet-rich plasma is effective and safe for increasing hair density in androgenetic alopecia, showing significant improvement compared to placebo at 3 and 6 months.
2 citations
,
July 2023 in “Journal of cosmetic dermatology” In this study, JAK inhibitors like baricitinib and ruxolitinib were found to be more effective and caused fewer discontinuations due to adverse events in adults with alopecia areata compared to therapies like dupilumab and apremilast, highlighting the need for more high-quality comparative trials.
2 citations
,
June 2023 in “Skin Research and Technology” This study reviewed 39 studies with 3204 patients to identify characteristic trichoscopic findings in alopecia areata, highlighting yellow and black dots, broken, short vellus, and tapering hairs as key indicators. It found no single diagnostic trichoscopic finding but observed trichoscopy's utility in monitoring treatment response.
2 citations
,
May 2022 in “Tropical Journal of Pharmaceutical Research” In this meta-analysis, probiotic consumption in rheumatoid arthritis patients significantly improved disease activity scores and reduced certain inflammatory cytokines, but did not affect ACR20 response or other measured parameters compared to placebo.
2 citations
,
April 2019 in “Acta medica Philippina/Acta Medica Philippina” This study observed that patients with alopecia areata had significantly lower serum 25-hydroxyvitamin D levels than healthy controls, with a trend toward even lower levels in more severe cases.
1 citations
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November 2025 in “Journal of Managed Care & Specialty Pharmacy” This study concluded that while CDK4/6 inhibitors, used to treat HR+ HER2- metastatic breast cancer, generally did not worsen health-related quality of life, they were associated with increased patient-reported issues like diarrhea and hair loss upset.
1 citations
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March 2025 in “JAAD reviews.” This study found that hypertrichosis occurs in 23% of patients using minoxidil for alopecia, but only 0.49% discontinued treatment due to this side effect.
1 citations
,
June 2023 in “Curēus” In this study, researchers found that 24.7% of female medical students were diagnosed with PCOS, significantly affecting their academic success and social interactions due to symptoms like BMI abnormalities and acne, suggesting that educators should enhance support and awareness to address these challenges.