Relationship Between Early-Onset Androgenetic Alopecia and Metabolic Syndrome: Systematic Review and Meta-Analysis

August 2017 in “ 韓方眼耳鼻咽喉皮膚科學會誌 = The journal of Korean Medicine Ophthalmology & Otolaryngology & Dermatology ”

장진영, Young-Joon Yoon

androgenetic alopecia early-onset androgenetic alopecia metabolic syndrome case-control studies systematic review meta-analysis AGA MetS

TLDR Early-onset male baldness is significantly linked to a higher risk of metabolic syndrome.

The study conducted in 2017 aimed to verify the relationship between early-onset androgenetic alopecia (AGA) and metabolic syndrome (MetS). The researchers used data from 13 case-control studies related to the MetS of early-onset alopecia patients for a systematic review and meta-analysis. The most common bias found in these studies was participant selection bias. The systematic review found a significant association between early-onset AGA and MetS in 10 out of 13 articles (76.9%). The meta-analysis revealed that early-onset male AGA was associated with an increased risk of metabolic syndrome (OR: 3.73, 95% CI:2.49 –5.61). The conclusion was that early-onset male AGA is significantly associated with MetS, suggesting that patients with early-onset male AGA should consider preventive treatment to reduce the risk of MetS and associated problems.

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