Relationship Between Early-Onset Androgenetic Alopecia and Metabolic Syndrome: Systematic Review and Meta-Analysis

The study conducted in 2017 aimed to verify the relationship between early-onset androgenetic alopecia (AGA) and metabolic syndrome (MetS). The researchers used data from 13 case-control studies related to the MetS of early-onset alopecia patients for a systematic review and meta-analysis. The most common bias found in these studies was participant selection bias. The systematic review found a significant association between early-onset AGA and MetS in 10 out of 13 articles (76.9%). The meta-analysis revealed that early-onset male AGA was associated with an increased risk of metabolic syndrome (OR: 3.73, 95% CI:2.49 –5.61). The conclusion was that early-onset male AGA is significantly associated with MetS, suggesting that patients with early-onset male AGA should consider preventive treatment to reduce the risk of MetS and associated problems.