149 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
41 citations,
September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
36 citations,
April 2013 in “Cell and Tissue Research” Bone-marrow and epidermal stem cells help heal wounds differently, with bone-marrow cells aiding in blood vessel formation and epidermal cells in hair growth.
26 citations,
January 2019 in “Experimental Dermatology” Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
23 citations,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
20 citations,
September 2020 in “Journal of Translational Medicine” Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
12 citations,
November 2020 in “Journal of Dermatological Science” Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.
3 citations,
January 2023 in “Physiological Research” Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.
1 citations,
April 2016 in “Journal of Investigative Dermatology” Blocking Prostaglandin D₂ may help treat hair loss.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
12 citations,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
3 citations,
April 2019 in “Stem cells international” Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
174 citations,
November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
73 citations,
August 2011 in “Stem Cell Research” Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
69 citations,
April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
1 citations,
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.
December 2023 in “International journal of multidisciplinary research and analysis” SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
4 citations,
May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
263 citations,
February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
131 citations,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
36 citations,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
6 citations,
July 2022 in “World journal of stem cells” Using extracellular vesicles from stem cells can help hair grow by affecting scalp cells and hair follicles.
3 citations,
April 2022 in “Frontiers in Physiology” Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
2 citations,
January 2017 in “AIMS cell and tissue engineering” Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
April 2024 in “Biomolecules” Exosomal miRNAs from stem cells can help improve skin health and delay aging.
March 2024 in “Biomedicines” Mesenchymal stem cells show promise for effective skin repair and regeneration.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.