28 citations,
September 2021 in “EMBO reports” Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.
28 citations,
October 2013 in “Cornea” Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.
10 citations,
November 2018 in “Nature Biotechnology” Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
109 citations,
September 2011 in “Human molecular genetics online/Human molecular genetics” New treatments targeting specific genes show promise for treating keratin disorders.
14 citations,
May 2022 in “Asian Journal of Pharmaceutical Sciences” New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.
6 citations,
July 2017 in “Clinics in Plastic Surgery” The document concludes that individualized reconstruction plans are essential for improving function and appearance after head and neck burns.
1 citations,
July 2021 in “IntechOpen eBooks” Environmental factors can cause mutations in skin proteins, leading to skin disorders.
3 citations,
January 2023 in “American journal of physiology. Cell physiology” Inward rectifier potassium channels are important in many body functions and diseases, and could be potential drug targets.
105 citations,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
Different types of sun exposure damage skin cells and immune cells, with chronic exposure leading to more severe and lasting damage.
44 citations,
August 2008 in “Plant journal” D'orenone stops root hair growth by disrupting auxin transport, but adding auxin can reverse this.
False daisy is a medicinal herb with many health benefits, including hair growth promotion.
2 citations,
June 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Epigenetic factors play a crucial role in skin health and disease.
39 citations,
September 2012 in “Human Reproduction” Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.
29 citations,
October 2019 in “Journal of dermatological science” Studying premature aging syndromes helps understand human aging and suggests potential treatments.
114 citations,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
13 citations,
May 2011 in “Bioorganic & Medicinal Chemistry” Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
39 citations,
May 2011 in “Human Immunology” Genetics play a role in acne, but how exactly they contribute is not fully understood.
14 citations,
July 2021 in “Biomedicines” Platelet-rich treatments can help improve wound healing and tissue repair.
140 citations,
November 2018 in “Pharmacology & Therapeutics” Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.
April 2024 in “Journal of cosmetic dermatology” Platelet-rich fibrin might be a promising treatment for hair loss, but more research is needed to confirm its effectiveness.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
11 citations,
December 2006 in “Expert Review of Dermatology” Dermoscopy is becoming essential for diagnosing skin conditions and is expected to be a standard tool for dermatologists.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
168 citations,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
32 citations,
March 2021 in “Journal of endocrinological investigation” Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
December 2022 in “Türk biyokimya dergisi” The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.
5 citations,
January 2016 in “Journal of The American Academy of Dermatology” Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Aging causes changes in scalp cells that can negatively affect hair health.