Hereditary Chorea Associated With and Aggravated by Systemic Lupus Erythematosus
June 2021
in “
Cureus
”
Studysummary This case report describes the first known instance of hereditary choreiform disorder associated with and aggravated by systemic lupus erythematosus, highlighting the need for vigilance in diagnosing co-existing autoimmune conditions.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
This case report described a 19-year-old girl from Balochistan, Pakistan, with hereditary chorea, likely Huntington's disease (HD), which was aggravated by systemic lupus erythematosus (SLE). Despite the lack of genetic testing due to financial constraints, the clinical presentation strongly suggested HD. The patient met the American College of Rheumatology criteria for SLE, confirmed by laboratory tests. The report emphasized the importance of recognizing comorbid autoimmune conditions like SLE in patients with hereditary choreiform disorders and highlighted the need for better understanding and management of these comorbidities. This was the first reported case of HD associated with SLE from Baluchistan, Pakistan.
