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Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Young adults have about 230,000 tactile nerve fibers, decreasing 5-8% per decade with age.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.