7 citations
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September 2021 in “Antimicrobial Agents and Chemotherapy” This study found that olorofim demonstrated potent in vitro and in vivo antifungal activity against dermatophytes, resolving skin lesions in a guinea pig model similar to clotrimazole, suggesting it may be a promising treatment for dermatophytosis.
2 citations
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August 2024 in “Heliyon” This study concluded that Metformin may be suitable for prophylaxis or mild COVID-19, while a combination of Oseltamivir, Tamoxifen, and Dexamethasone could benefit moderate to severe cases, highlighting the need for more trials on other drug candidates.
86 citations
,
January 2019 in “Frontiers in Immunology” The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
31 citations
,
October 1992 in “Journal of Clinical Pharmacy and Therapeutics” This study found that while many drugs are reported to cause hair color changes, substantial evidence supporting a true relationship exists mainly for chloroquine and certain cancer chemotherapeutic agents.
2 citations
,
June 2020 in “BMC Health Services Research” This study found that after a health warning, off-label flutamide use by women reduced significantly in Spain, although misuse among ambulatory patients remains an issue.
September 2012 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that D-004, a lipid extract from royal palm fruit, has a moderate antidepressant effect in mice, which may help treat depressive symptoms in patients with benign prostatic hyperplasia.
September 2018 in “Dermatologic Therapy” This article is a commentary on another piece about the clinical efficacy of oral finasteride and reports no new results.
9 citations
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March 2024 in “Journal of Biomaterials Applications” This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.
1 citations
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July 2020 in “Reviews in separation sciences” This study developed a simple method to determine finasteride, indapamide, and tiemonium methylsulfate in pharmaceuticals by using their ability to form silver nanoparticles measurable via spectrophotometry.
42 citations
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August 2012 in “Psychoneuroendocrinology” Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
4 citations
,
November 1984 in “JAMA” This case report describes a 61-year-old woman with Sjögren's syndrome who experienced multiple episodes of aseptic meningitis linked to trimethoprim-sulfamethoxazole and trimethoprim use.
January 2021 in “International Journal of Advanced Research in Medicine” This study observed that propranolol, flunarizine, and divalproex sodium were equally effective in managing migraine across a three-month period in a group of 84 patients, with various side effects noted among the drug groups.
This study found that mycophenolate mofetil was well tolerated and effective as a second-line treatment for autoimmune hepatitis in patients who were intolerant to azathioprine.
18 citations
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April 2011 in “Neuropharmacology” This study found that metyrapone and etomidate provide dose-dependent anticonvulsant effects against seizures, with delayed effectiveness linked to increased neurosteroid levels.
This compilation lists potential side effects, drug interactions, and trade names of various dermatological and antiretroviral medications, but it reports no original research findings.
April 2016 in “Expert opinion on orphan drugs” This review explores current therapeutic options for frontal fibrosing alopecia, noting the use of finasteride, topical tacrolimus, hydroxychloroquine, and excimer laser in managing the condition, but reports no new clinical results.
16 citations
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June 2017 in “JAMA Dermatology” Thalidomide works best for skin lupus not helped by antimalarials, but has many side effects; other treatments are less effective, especially if patients also have systemic lupus.
January 2026 in “RSC Advances” This study used a zebrafish model and advanced mass spectrometry to identify 11 metabolites of epristeride, revealing significant effects on purine metabolism and aromatic amino acid biosynthesis, which may aid in developing anti-doping detection methods.
36 citations
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November 1995 in “Clinical endocrinology” This study found that a low dose of flutamide, both alone and combined with an oral contraceptive, effectively reduced hirsutism in women, with the combination showing more lasting effects post-treatment.
109 citations
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March 2011 in “Journal of controlled release” This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.
65 citations
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April 1999 in “Journal of Parasitology” This study found that all lesions in mice treated with a new topical formulation, WR 279,396, healed completely without relapse, outperforming other formulations and showing no toxicity.
61 citations
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March 1990 in “Clinical pharmacology and therapeutics/Clinical pharmacology & therapeutics” In this study, albendazole treatment in patients with hydatid disease was associated with decreased microsomal enzyme function and induced its own metabolism, but also showed potential hepatotoxicity and severe side effects, necessitating careful monitoring.
January 2024 in “Arquivos de Neuro-Psiquiatria” This study reviewed various treatments for migraines and found that both classic medications, such as triptans and beta-blockers, and newer options like CGRP inhibitors, are effective, while non-pharmacological approaches provide moderate relief and are highly effective preventively, though accessibility can be an issue.
8 citations
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November 1990 in “International Journal of Dermatology” This study reports that telogen effluvium, a form of hair loss, may be associated with the use of albendazole therapy.
30 citations
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March 2011 in “Australasian Journal of Dermatology” This case report found that a woman's hair loss, which progressed while using spironolactone and topical minoxidil, reversed after switching to flutamide therapy.
30 citations
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December 1999 in “International Journal of Dermatology” In this uncontrolled study, ivermectin treatment for scabies resulted in the resolution of symptoms and negative skin scrapings in most patients at follow-ups.
6 citations
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November 2018 in “Antimicrobial agents and chemotherapy (Print)” This study found that fluconazole was associated with telogen effluvium in both a rat model and human patients, although retinoic acid levels were not identified as a causal factor.
November 2015 in “Ankara Medical Journal” This study concluded that weekly 5 mg folate supplementation is adequate for preventing methotrexate toxicity in rheumatoid arthritis patients, with no observed advantage to higher daily dosing after six months.
July 1996 in “Annals of Internal Medicine” This correspondence reported significant variability between quantitative PCR and bDNA assays for measuring Hepatitis C virus RNA in high-titer specimens, challenging the reliability of the Chiron assay.