research Molecular Genetics of Inherited Disorders of Epidermal Keratins
Mutations in keratin genes cause skin disorders, but new treatments show promise.
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research Surgical Treatment of Secondary Cicatricial Alopecia of Scalp and Eyebrow
Surgical methods for hair loss due to scarring should be chosen based on the size, location, and shape of the area, with most patients seeing good results.
research Spironolactone Reduces Hair Growth in Idiopathic Hirsutism
Spironolactone reduces hair growth in women with unexplained excessive hairiness.
research Composite Double-Layer Microneedle Loaded With Traditional Chinese Medicine for the Treatment of Androgenic Alopecia
Microneedles with traditional Chinese medicine can help regrow hair in androgenic alopecia.
research Using Light to Study Sound: Stimulating Hair Cells With Photonic Pressure
Light can be used to stimulate ear hair cells, improving speed and consistency over previous methods.
research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
The study revealed that the opioid system, particularly through delta opioid receptors (DOR), played a significant role in regulating cutaneous mechanosensation, including both touch and pain. DORs were found on myelinated mechanoreceptors associated with structures like Meissner corpuscles and Merkel cell-neurite complexes. These receptors also appeared on a subset of nociceptors coexpressing mu and delta opioid receptors. Activation of DORs at the central terminals of these mechanoreceptors inhibited synaptic input to the spinal dorsal horn by blocking voltage-gated calcium channels. This mechanism suggested that targeting DOR could be a potential strategy for managing injury-induced mechanical hypersensitivity.
research Signaling in the Stem Cell Niche: Regulating Cell Fate, Function, and Plasticity
The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
research Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology
Metabolic signals and cell shape influence how cells develop and change.
research Nanotribological Characterization of Human Hair and Skin Using Atomic Force Microscopy
The research improved understanding of hair and skin properties across different ethnicities and conditions.
research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Multifunctional DNA Hydrogels with Hydrocolloid-Cotton Structure for Regeneration of Diabetic Infectious Wounds
The DNA hydrogel helps heal diabetic wounds by absorbing fluids, warming, sticking to tissue, killing bacteria, and aiding tissue and hair regrowth.
research Biomaterials for In Situ Tissue Regeneration: Development and Perspectives
Smart biomaterials that guide tissue repair are key for future medical treatments.
research Two Distinct Signaling Pathways in Hair Cycle Induction: Stat3-Dependent and Independent Pathways
There are two ways to start hair growth: one needs Stat3 and the other does not, but both need PI3K activation.
research The Facial Adipose Tissue: A Revision
Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.
research Effect of Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate) Nanofiber Matrices Cocultured With Hair Follicular Epithelial and Dermal Cells for Biological Wound Dressing
PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.
research The Structural and Functional Aspects of Hair Cell Regeneration in the Chick as a Result of Exposure to Intense Sound
Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.
research Engineering Pro-Regenerative Hydrogels for Scarless Wound Healing
Hydrogels could lead to better treatments for wound healing without scars.
research Hair Structure Anatomy And Comparative Anatomy Dedicated To The Memory Of The Late Dr. R. E. Rivett Whose Untimely Death Prevented His Role In Co-Authorship
Human hair is complex and grows in cycles starting from embryonic life.
research Chronological ageing of human hair keratin fibres
The study examined very long human hair (over 2.4 m) to understand the natural ageing process of hair keratin fibers using various evaluation methods. It focused on hair that had not been exposed to chemical treatments like bleaching or dyeing. The findings showed that ageing begins with the abrasion of the cuticle while the cortex remains intact up to about 1 m from the root, maintaining shine, hydrophobicity, and friction characteristics. Beyond this point, significant cuticle damage occurs, correlating with a decline in ceramides, 18-Methyl Eicosanoic Acid (18-MEA), and keratin-associated proteins, leading to a decrease in mechanical and optical properties. This research provided a detailed 'damage scale' of hair ageing, which could aid in developing targeted hair care products.
research Enhanced Cutaneous Wound Healing by Functional Injectable Thermo-Sensitive Chitosan-Based Hydrogel Encapsulated Human Umbilical Cord-Mesenchymal Stem Cells
A new hydrogel with stem cells from human umbilical cords improves skin wound healing and reduces inflammation.
research Effect of Ethnicity and Treatments on In Situ Tensile Response and Morphological Changes of Human Hair Characterized by Atomic Force Microscopy
Different ethnicities and treatments affect human hair strength and structure.
research Effect of Varied Hair Protein Fractions on the Gel Properties of Keratin/Chitosan Hydrogels for Use in Tissue Engineering
Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.
research A Detective Look at Hair Biopsies from African-American Patients
Recognizing specific features of African-American hair can help diagnose hair loss conditions.
research Traumatic Alopecia
Early diagnosis and treatment are crucial to prevent permanent hair loss from scalp trauma.
research Trichorrhexis Nodosa
The study on trichorrhexis nodosa (TN) involved 49 patients, with 26 experiencing scalp hair involvement, and 20 of these cases linked to excessive hair trauma. Additionally, 23 patients had TN in genito-inguinocrural or multiple sites, all experiencing pruritus. The condition often improved with less traumatic hair care or pruritus control. The research did not support the theory of TN being a metabolic defect, as shown by urine chromatography and hair analysis. The findings highlighted trauma as a significant factor, with in vitro experiments reproducing TN through mechanical stress, identifying it as a common cause of unexplained hair loss.
research Design of a RADA16-Based Self-Assembling Peptide Nanofiber Scaffold for Biomedical Applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Electrospun Fibrous Sponge via Short Fiber for Mimicking 3D Extracellular Matrix
The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.
research Cutaneous Manifestations of Eating Disorders
Eating disorders can cause skin problems that need treating the underlying condition for better health.
research ROS-Eliminating Carboxymethyl Chitosan Hydrogel to Enhance Burn Wound-Healing Efficacy
The hydrogel speeds up burn wound healing and promotes tissue regeneration.