Trichorrhexis Nodosa: Study on Hair Involvement and Trauma

November 1966 in “ Archives of Dermatology ”

Marvin E. Chernosky

The study on trichorrhexis nodosa (TN) involved 49 patients, with 26 experiencing scalp hair involvement, and 20 of these cases linked to excessive hair trauma. Additionally, 23 patients had TN in genito-inguinocrural or multiple sites, all experiencing pruritus. The condition often improved with less traumatic hair care or pruritus control. The research did not support the theory of TN being a metabolic defect, as shown by urine chromatography and hair analysis. The findings highlighted trauma as a significant factor, with in vitro experiments reproducing TN through mechanical stress, identifying it as a common cause of unexplained hair loss.

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