Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study suggests that infiltrating M2 macrophages promote wound-induced hair neogenesis in mice by producing growth factors that activate the wnt signaling pathway during the late phase of wound healing.

Patients with central centrifugal cicatricial alopecia may have a higher risk of breast and colorectal cancer.

This study found that applying a formulation derived from Bacopa procumbens significantly promoted hair growth, pigmentation, and follicular cycle acceleration in mice compared to minoxidil, potentially offering a new therapeutic approach for hair health.

In this study, among 2,000 patients with alopecia universalis, mesotherapy combined with systemic treatments like BMI, JAK inhibitors, and adalimumab showed the highest success in hair regrowth, particularly for children, with the combination therapy group achieving a 42% positive response rate.

This review explores the potential of cell-mediated drug delivery systems in dermatology, highlighting their ability to target inflamed or diseased skin while discussing applications in diseases like atopic dermatitis and melanoma, along with challenges such as immunogenicity and manufacturing.

This study found that inhibiting the enzyme ornithine decarboxylase (ODC) prevented UVB-induced basal cell carcinomas in a mouse model, suggesting ODC is a potential target for chemoprevention strategies.

In this study, BECD-treated wavy hair showed reduced undulation and improved straightening after drying, as BECD enhanced the contraction and rearrangement of molecular chains in non-keratin proteins, unlike untreated hair, which retained its wavy structure.

This study found that α-MSH administration before skin wounding in adult mice reduced inflammation and scar area, suggesting a potential pathway to more regenerative healing.

This review discusses current uses and advancements in mesenchymal stem cell-derived conditioned media as a potential regenerative therapy but does not present new clinical findings.

This review discusses the role of acyl-CoA binding protein (ACBP) in the epidermal barrier, noting that its disruption in mice is linked to skin and fur abnormalities; it reports no new clinical results.

This study found that MRL/MpJ mouse dorsal skin wounds heal with similar scar formation and collagen deposition as C57bl/6 and Balb/c mice.

This study found that the Plcd3(mNab) mutation in mice worsens the alopecia caused by Plcd1 loss, suggesting synergistic effects between Plcd1 and Plcd3 on hair follicle health.

This review discusses the interactions between melanocyte stem cells and their niche in hair regeneration and repair, but reports no new results; recent studies on molecular pathways are highlighted.

This study found that deleting the Mad2l1 gene in mice leads to rapid onset of acute lymphoblastic leukemia and liver cancer due to induced chromosomal instability.

This study found that women with polycystic ovary syndrome had worse meibomian gland morphology and ocular surface conditions compared to healthy controls, as observed through non-contact meibography.

This study found that a significant number of boreal woodland caribou in NE British Columbia showed symptoms of trace mineral deficiencies and exposure to various pathogens, with substantial winter tick infestations affecting a majority of individuals.

This research describes methods to activate melanocyte stem cells during hair follicle regeneration and to isolate melanocytes from neonatal mouse skin, with the aim of studying melanogenesis for potential clinical applications.

This study suggests that differential expression of miRNAs in hair follicles from the frontal and occipital scalp may contribute to the androgen-dependent changes seen in male pattern baldness.

In this study, Mpzl3-/- mice developed severe seborrhea-like dermatitis with skin inflammation, indicating MPZL3's role in the skin condition's development, independent of adaptive immunity.

This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.

This case report highlights a rare instance of CD8-positive hypopigmented mycosis fungoides causing alopecia areata-like changes, emphasizing the necessity of scalp biopsy in such presentations.

In a randomized clinical trial, Robinson et al found that patients with melanoma and their partners could effectively perform skin self-examinations after participating in a 30-minute structured skills training, potentially aiding early detection of additional melanomas.

This study observed that dalpiciclib is associated with fewer adverse events like diarrhea and hepatotoxicity compared to other CDK4/6 inhibitors, potentially offering better patient-perceived safety and quality of life.

This study found that coadministration of pimecrolimus may interfere with the therapeutic efficacy of mesenchymal stem cell therapy in atopic dermatitis.

This case report highlights a female patient with familial partial lipodystrophy who showed significant improvement in liver stiffness after starting leptin replacement therapy.

In this study with stumptailed macaques, topical minoxidil successfully induced hair regrowth on bald scalps and prevented baldness on non-bald scalps, with no observed side effects over nearly three years.

In this study, human hair dermal papilla cells were incubated with varying concentrations of umbilical cord-derived mesenchymal stem cell exosomes or minoxidil, and cell proliferation was assessed, showing significant results compared to the control.